Due to their critical functions in cell sensing and signal processing, membrane proteins are
highly preferred as pharmacological targets, and antibody drugs constitute the fastest …

Selections of yeast-displayed ligands on mammalian cell monolayers benefit from high
target expression and nanomolar affinity, which are not always available. Prior work …

Membrane proteins are favored drug targets and antibody therapeutics represent the fastest-
growing category of pharmaceuticals. However, there remains a need for rapid and effective …

Synthetic cell–cell interaction systems can be useful for understanding multicellular
communities or for screening binding molecules. We adapt a previously characterized set of …

High-throughput protein selection methods are a cornerstone for protein engineering and
pharmaceutical development. Traditional high-throughput selection strategies rely largely on …

A rapid and effective method to identify disease-specific antibodies from clinical patients is
important for understanding autoimmune diseases and for the development of effective …

A rapid and effective method to identify disease-specific antibodies from clinical patients is
important for understanding autoimmune diseases and for the development of effective …

Cancer is characterized by genetic mutations which interfere with the complex, well-
regulated signaling pathways governing cell behavior. When certain mutations accumulate …

Engineered protein ligands with specific, high-affinity binding to a biomarker that are
differentially expressed in a disease state have been applied in a variety of therapeutic and …