The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
[HTML][HTML] Childhood diarrhoeal diseases in developing countries
Diarrhoeal diseases collectively constitute a serious public health challenge globally,
especially as the leading cause of death in children (after respiratory diseases). Childhood …
especially as the leading cause of death in children (after respiratory diseases). Childhood …
[HTML][HTML] Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017 …
SL James, D Abate, KH Abate, SM Abay, C Abbafati… - The Lancet, 2018 - thelancet.com
Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study
2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and …
2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and …
[HTML][HTML] Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings …
Background Enteropathogen infections in early childhood not only cause diarrhoea but
contribute to poor growth. We used molecular diagnostics to assess whether particular …
contribute to poor growth. We used molecular diagnostics to assess whether particular …
[PDF][PDF] Global expenditure on health: public spending on the rise?
World Health Organization - 2021 - apps.who.int
Public spending on the rise? 2021 Page 1 Global expenditure on health: Public spending on the
rise? GLOBAL REPORT Page 2 Page 3 Global expenditure on health: Public spending on the …
rise? GLOBAL REPORT Page 2 Page 3 Global expenditure on health: Public spending on the …
Aetiology and incidence of diarrhoea requiring hospitalisation in children under 5 years of age in 28 low-income and middle-income countries: findings from the …
AL Cohen, JA Platts-Mills, T Nakamura, DJ Operario… - BMJ global …, 2022 - gh.bmj.com
Introduction Diarrhoea remains a leading cause of child morbidity and mortality.
Systematically collected and analysed data on the aetiology of hospitalised diarrhoea in low …
Systematically collected and analysed data on the aetiology of hospitalised diarrhoea in low …
[HTML][HTML] The implications of three major new trials for the effect of water, sanitation and hygiene on childhood diarrhea and stunting: a consensus statement
Background Three large new trials of unprecedented scale and cost, which included novel
factorial designs, have found no effect of basic water, sanitation and hygiene (WASH) …
factorial designs, have found no effect of basic water, sanitation and hygiene (WASH) …
[HTML][HTML] The Shigella Vaccines Pipeline
CA MacLennan, S Grow, L Ma, AD Steele - Vaccines, 2022 - mdpi.com
Shigella is the leading cause of global diarrheal deaths that currently lacks a licensed
vaccine. Shigellosis drives antimicrobial resistance and leads to economic impact through …
vaccine. Shigellosis drives antimicrobial resistance and leads to economic impact through …
[HTML][HTML] Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access
I Khalil, R Walker, CK Porter, F Muhib, R Chilengi… - Vaccine, 2021 - Elsevier
Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes
substantial morbidity and mortality predominantly in paediatric populations in low-and …
substantial morbidity and mortality predominantly in paediatric populations in low-and …
[HTML][HTML] Childhood vaccines and antibiotic use in low-and middle-income countries
Vaccines may reduce the burden of antimicrobial resistance, in part by preventing infections
for which treatment often includes the use of antibiotics,,–. However, the effects of …
for which treatment often includes the use of antibiotics,,–. However, the effects of …