Introduction: Breast cancer subtypes are currently defined by a combination of morphologic,
genomic, and proteomic characteristics. These subtypes provide a molecular portrait of the …

In anatomic pathology, immunohistochemistry (IHC) serves as a diagnostic and prognostic
method for identification of disease markers in tissue samples that directly influences …

Obesity favours the occurrence of locally disseminated prostate cancer in the periprostatic
adipose tissue (PPAT) surrounding the prostate gland. Here we show that adipocytes from …

Abstract Development of highly vascular dermal tissue-engineered skin substitutes with
appropriate mechanical properties and cellular cues is in need for significant advancement …

Abstract American Cutaneous Leishmaniasis (ACL) is a zoonosis caused by Leishmania
protozoa. The ACL chemotherapy available is unsatisfactory motivating researches to seek …

The lack of specificity of traditional cytotoxic drugs has triggered the development of
anticancer agents that selectively address specific molecular targets. An intrinsic property of …

B cell-activating factor (BAFF) is an essential cytokine in primary Sjögren's syndrome (pSS)
physiopathology. It has been reported that pSS patients develop germinal center-like (GC …

American cutaneous leishmaniasis is a zoonotic disease caused by protozoans of the genus
Leishmania. The treatment of cutaneous leishmaniasis is unsatisfactory, thus, much …

Bacterial colonisation of the gut is involved in the development of colitis-associated
colorectal cancer. However, it remains unclear how the gut microbiota dynamically shifts …

Articular cartilage damage represents one of the most perplexing clinical problems of
musculoskeletal therapeutics due to its limited self-repair and regenerative capabilities. In …