Noninvasive biomarkers in NAFLD and NASH—current progress and future promise

VWS Wong, LA Adams, V de Lédinghen… - Nature reviews …, 2018 - nature.com
Nonalcoholic fatty liver disease (NAFLD) affects 25% of the global adult population and is
the most common chronic liver disease worldwide. Nonalcoholic steatohepatitis (NASH) is …

[HTML][HTML] Limitations of non-invasive tests for assessment of liver fibrosis

K Patel, G Sebastiani - JHEP Reports, 2020 - Elsevier
The diagnostic assessment of liver injury is an important step in the management of patients
with chronic liver disease (CLD). Although liver biopsy is the reference standard for the …

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update

A Berzigotti, E Tsochatzis, J Boursier, L Castera… - Journal of …, 2021 - Elsevier
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

Non-invasive tests accurately stratify patients with NAFLD based on their risk of liver-related events

J Boursier, H Hagström, M Ekstedt, C Moreau… - Journal of …, 2022 - Elsevier
Background & Aims Previous studies on the prognostic significance of non-invasive liver
fibrosis tests in non-alcoholic fatty liver disease (NAFLD) lack direct comparison to liver …

Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update

SK Sarin, M Kumar, GK Lau, Z Abbas, HLY Chan… - Hepatology …, 2016 - Springer
Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …

Noninvasive tests accurately identify advanced fibrosis due to NASH: baseline data from the STELLAR trials

QM Anstee, EJ Lawitz, N Alkhouri, VWS Wong… - Hepatology, 2019 - journals.lww.com
Accurate noninvasive tests (NITs) are needed to replace liver biopsy for identifying
advanced fibrosis caused by nonalcoholic steatohepatitis (NASH). We analyzed screening …

AASLD Practice Guideline on blood-based noninvasive liver disease assessment of hepatic fibrosis and steatosis

RK Sterling, K Patel, A Duarte-Rojo, SK Asrani… - Hepatology, 2025 - journals.lww.com
Chronic liver disease (CLD) leads to liver fibrosis; it is associated with approximately two
million annual deaths worldwide and is an enormous health burden.[1, 2] The majority of …

[PDF][PDF] Assessment of biopsy‐proven liver fibrosis by two‐dimensional shear wave elastography: An individual patient data‐based meta‐analysis

E Herrmann, V de Lédinghen, C Cassinotto… - …, 2018 - Wiley Online Library
Two‐dimensional shear wave elastography (2D‐SWE) has proven to be efficient for the
evaluation of liver fibrosis in small to moderate‐sized clinical trials. We aimed at running a …

[HTML][HTML] EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis

European Association for the Study of the Liver - Journal of hepatology, 2015 - Elsevier
Liver fibrosis is part of the structural and functional alterations in most chronic liver diseases.
It is one of the main prognostic factors as the amount of fibrosis is correlated with the risk of …

[PDF][PDF] Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease

VWS Wong, J Vergniol, GLH Wong, J Foucher… - …, 2010 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in
affluent countries. Accurate noninvasive tests for liver injury are urgently needed. The aim of …