[HTML][HTML] Recent advances in biological nanopores for nanopore sequencing, sensing and comparison of functional variations in MspA mutants

H Bhatti, R Jawed, I Ali, K Iqbal, Y Han, Z Lu, Q Liu - Rsc Advances, 2021 - pubs.rsc.org
Biological nanopores are revolutionizing human health by the great myriad of detection and
diagnostic skills. Their nano-confined area and ingenious shape are suitable to investigate a …

A nanopore sensor for multiplexed detection of short polynucleotides based on length-variable, poly-arginine-conjugated peptide nucleic acids

L Mereuta, A Asandei, I Dragomir, J Park… - Analytical …, 2022 - ACS Publications
Real-time and easy-to-use detection of nucleic acids is crucial for many applications,
including medical diagnostics, genetic screening, forensic science, or monitoring the onset …

Single‐molecule, hybridization‐based strategies for short nucleic acids detection and recognition with nanopores

T Luchian, L Mereuta, Y Park, A Asandei… - Proteomics, 2022 - Wiley Online Library
DNA nanotechnology has seen large developments over the last 30 years through the
combination of detection and discovery of DNAs, and solid phase synthesis to increase the …

[HTML][HTML] Sequence-specific detection of single-stranded DNA with a gold nanoparticle-protein nanopore approach

L Mereuta, A Asandei, IS Dragomir, IC Bucataru… - Scientific reports, 2020 - nature.com
Fast, cheap and easy to use nucleic acids detection methods are crucial to mitigate adverse
impacts caused by various pathogens, and are essential in forensic investigations, food …

[HTML][HTML] Machine learning to improve the sensing of biomolecules by conical track-etched nanopore

N Meyer, JM Janot, M Lepoitevin, M Smietana… - Biosensors, 2020 - mdpi.com
Single nanopore is a powerful platform to detect, discriminate and identify
biomacromolecules. Among the different devices, the conical nanopores obtained by the …

Synthetic Receptor Based on a Peptide Antibiotic-Functionalized Chimera for Hybridization-Based Polynucleotide Detection

L Mereuta, A Asandei, I Schiopu, J Park… - … Applied Materials & …, 2023 - ACS Publications
Nanopores offer highly sensitive, low-cost, and single-molecule sensing capabilities, and
the societal impact of this approach is best captured by the advent of nanopore-based DNA …

Recognition of single‐point mutation using a biological nanopore

P Liu, R Kawano - Small Methods, 2020 - Wiley Online Library
Here the recognition of a single‐point mutation in oligonucleotides is described by using
nanopore measurements. The translocation behavior of a series of mutated DNA strands …

Controlling DNA Fragments Translocation across Nanopores with the Synergic Use of Site-Directed Mutagenesis, pH-Dependent Charge Tuning, and Electroosmotic …

L Mereuta, H Bhatti, A Asandei… - … Applied Materials & …, 2024 - ACS Publications
Biological and solid-state nanopores are at the core of transformative techniques and
nanodevices, democratizing the examination of matter and biochemical reactions at the …

Differentiating a least-stable single nucleotide mismatch in DNA via metal ion-mediated base pairing and using thioflavin T as an extrinsic fluorophore

S Pramanik, L Khamari… - The Journal of Physical …, 2021 - ACS Publications
Monitoring the DNA dynamics in solution has great potential to develop new nucleic acid-
based sensors and devices. With spectroscopic approaches, both at the ensemble average …

Simultaneous Dual-Site Identification of 5mC/8oG in DNA Triplex Using a Nanopore Sensor

W Li, Y Wang, Y Xiao, M Li, Q Liu, L Liang… - … Applied Materials & …, 2022 - ACS Publications
DNA triplex participates in delivering site-specific epigenetic modifications critical for the
regulation of gene expression. Among these marks, 5mC with 8oG functions …