Cucurbituril‐based supramolecular polymers for biomedical applications

Z Wang, C Sun, K Yang, X Chen… - Angewandte Chemie …, 2022 - Wiley Online Library
Supramolecular polymers (SPs) have attracted broad interest because of their intriguing
features and functions. Host–guest interactions often impart tunable physicochemical …

Challenges and opportunities of functionalized cucurbiturils for biomedical applications

H Yin, Q Cheng, D Bardelang, R Wang - JACS Au, 2023 - ACS Publications
Cucurbit [n] uril (CB [n]) macrocycles (especially CB [5] to CB [8]) have shown exceptional
attributes since their discovery in 2000. Their stability, water solubility, responsiveness to …

[HTML][HTML] Host-guest chemistry in supramolecular theranostics

G Yu, X Chen - Theranostics, 2019 - ncbi.nlm.nih.gov
Macrocyclic hosts, such as cyclodextrins, calixarenes, cucurbiturils, and pillararenes, exhibit
unparalleled advantages in disease diagnosis and therapy over the past years by fully …

Molecular conjugation using non-covalent click chemistry

CL Schreiber, BD Smith - Nature Reviews Chemistry, 2019 - nature.com
Molecular conjugation refers to methods used in biomedicine, advanced materials and
nanotechnology to link two partners—from small molecules to large and sometimes …

Polymer nanocontainers for intracellular delivery

S Pottanam Chali, BJ Ravoo - … Chemie International Edition, 2020 - Wiley Online Library
Carriers for intracellular delivery are required to overcome limitations of therapeutic agents
such as low specificity, systemic toxicity, high clearance rate, and low therapeutic index …

Supramolecular nano drug delivery systems mediated via host-guest chemistry of cucurbit [n] uril (n= 6 and 7)

S Li, Y Gao, Y Ding, A Xu, H Tan - Chinese Chemical Letters, 2021 - Elsevier
As a novel family of macrocyclic molecules, cucurbit [n] urils (CB [n] s) have emerged as
promising building blocks of supramolecular nano drug delivery systems (SNDDS) in recent …

Supramolecular luminol–AIEgen nanoparticles for deep-tissue-inflammation imaging

J Chen, Q Huang, Q Wang, Y Ding, S Lu… - ACS Applied Nano …, 2022 - ACS Publications
Inflammation is one of the most common pathological processes involved in numerous
diseases. Thus, bioimaging of inflammation is of great significance for the diagnosis and …

Polymeric nanomedicine with “Lego” surface allowing modular functionalization and drug encapsulation

C Sun, H Zhang, S Li, X Zhang, Q Cheng… - … applied materials & …, 2018 - ACS Publications
Surface functionalization of nanoparticles (NPs) is of pivotal importance in nanomedicine.
However, current strategies often require covalent conjugation that involves laborious …

Nanocluster-based drug delivery and theranostic systems: Towards cancer therapy

AL Villela Zumaya, R Mincheva, JM Raquez… - Polymers, 2022 - mdpi.com
Over the last decades, the global life expectancy of the population has increased, and so,
consequently, has the risk of cancer development. Despite the improvement in cancer …

Facile preparation of cucurbit [6] uril-based polymer nanocapsules for targeted photodynamic therapy

C Sun, H Zhang, L Yue, S Li, Q Cheng… - ACS applied materials …, 2019 - ACS Publications
Covalently self-assembled polymer nanocapsules (NCs) based on cucurbit [6] uril have
been previously prepared and their applications in payload delivery and bioimaging have …