Messenger RNA (mRNA) is an emerging class of therapeutic agent for the prevention and
treatment of a wide range of diseases. The recent success of the two highly efficacious …

Circular RNAs (circRNAs) are RNAs with a unique circular structure that is generated from
back-splicing processes. These circular molecules were discovered more than 40 years ago …

Rationale: Osteoarthritis (OA) is the most common joint disease worldwide. Previous studies
have identified the imbalance between extracellular matrix (ECM) catabolism and anabolism …

Abstract clustered regularly interspaced short palindromic repeats (CRISPR)‐Cas systems
are increasingly used in biosensor development. However, directly translating recognition …

Messenger RNA (mRNA) vaccine development for preventive and therapeutic applications
has evolved rapidly over the last decade. The mRVNA vaccine has proven therapeutic …

Abstract Purpose of Review Circular RNAs (circRNAs) are RNA transcripts derived from
fragments of pre-messenger RNAs through a back-splicing process. An advantage that rises …

Abstract Objectives Circular RNAs (circRNAs) are noncoding RNAs that compete against
other endogenous RNA species, such as microRNAs, and have been implicated in many …

The relevance of circular RNAs (circRNAs) has been indicated in the progression of various
diseases. Nevertheless, the precise function of circRNAs in osteoarthritis (OA) remains to be …

Circular RNA (circRNA) forms closed loops via back-splicing in precursor mRNA, resisting
exonuclease degradation. In higher eukaryotes, protein-coding genes create circRNAs …

Abstract Background N 6-methyladenosine (m 6 A) is the most abundant modification of
RNA in eukaryotic cells and play critical roles in cancer. While most related studies focus on …