Therapy of mucormycosis

NV Sipsas, MN Gamaletsou, A Anastasopoulou… - Journal of Fungi, 2018 - mdpi.com
Despite the recent introduction of mold-active agents (posaconazole and isavuconazole), in
addition to amphotericin B products, to our armamentarium against mucormycosis, many …

Antifungal susceptibility testing: current approaches

EL Berkow, SR Lockhart… - Clinical Microbiology …, 2020 - Am Soc Microbiol
Although not as ubiquitous as antibacterial susceptibility testing, antifungal susceptibility
testing (AFST) is a tool of increasing importance in clinical microbiology laboratories. The …

Antifungal resistance in mucorales

E Dannaoui - International journal of antimicrobial agents, 2017 - Elsevier
The order Mucorales, which includes the agents of mucormycosis, comprises a large
number of species. These fungi are characterised by high-level resistance to most currently …

Epidemiology, modern diagnostics, and the management of mucorales infections

D Pham, AR Howard-Jones, R Sparks, M Stefani… - Journal of Fungi, 2023 - mdpi.com
Mucormycosis is an uncommon, yet deadly invasive fungal infection caused by the
Mucorales moulds. These pathogens are a WHO-assigned high-priority pathogen group, as …

Can we improve antifungal susceptibility testing?

C Durand, D Maubon, M Cornet, Y Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
Systemic antifungal agents are increasingly used for prevention or treatment of invasive
fungal infections, whose prognosis remains poor. At the same time, emergence of resistant …

Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase

R Caramalho, JDA Tyndall, BC Monk, T Larentis… - Scientific reports, 2017 - nature.com
Mucormycoses are emerging and potentially lethal infections. An increase of breakthrough
infections has been found in cohorts receiving short-tailed azoles prophylaxis (eg …

Mucormycosis: A hidden mystery of fungal infection, possible diagnosis, treatment and development of new therapeutic agents

MK Hussain, S Ahmed, A Khan, AJ Siddiqui… - European Journal of …, 2023 - Elsevier
Mucormycosis is a fungal infection which got worsens with time if not diagnosed and treated.
The current COVID-19 pandemic has association with fungal infection specifically with …

Antifungal susceptibly testing by concentration gradient strip Etest method for fungal isolates: a review

E Dannaoui, A Espinel-Ingroff - Journal of Fungi, 2019 - mdpi.com
Antifungal susceptibility testing is an important tool for managing patients with invasive
fungal infections, as well as for epidemiological surveillance of emerging resistance. For …

Combination therapy in Mucormycosis: Current evidence from the world literature, a mini review

DS Meena, D Kumar, GK Bohra - Journal of Medical Mycology, 2023 - Elsevier
The emergence of Mucorales infections is an urgent global public health threat rapidly
disseminating during the current COVID-19 pandemic. Invasive mucormycosis carries …

Mucorales: A systematic review to inform the World Health Organization priority list of fungal pathogens

CO Morrissey, HY Kim, K Garnham, A Dao… - Medical …, 2024 - academic.oup.com
Abstract The World Health Organization, in response to the growing burden of fungal
disease, established a process to develop a fungal priority pathogens list (FPPL). This …