[HTML][HTML] Aptamer microarrays—Current status and future prospects

M Witt, JG Walter, F Stahl - Microarrays, 2015 - mdpi.com
Microarray technologies are state of the art in biological research, which requires fast
genome, proteome and transcriptome analysis technologies. Often antibodies are applied in …

Development of an Efficient G‐Quadruplex‐Stabilised Thrombin‐Binding Aptamer Containing a Three‐Carbon Spacer Molecule

LJ Aaldering, V Poongavanam, N Langkjær… - …, 2017 - Wiley Online Library
The thrombin‐binding aptamer (TBA), which shows anticoagulant properties, is one of the
most studied G‐quadruplex‐forming aptamers. In this study, we investigated the impact of …

Binding modes of thrombin binding aptamers investigated by simulations and experiments

A Trapaidze, A Bancaud, M Brut - Applied Physics Letters, 2015 - pubs.aip.org
Thrombin binding aptamers HD1 and HD22 are the most studied aptamers, both for
therapeutic and sensing purposes. Yet, there is still no commercialized aptamer-based …

Enhancing DFT-based energy landscape exploration by coupling quantum mechanics and static modes

L Foulon, A Hémeryck, G Landa, M Brut - Physical Chemistry Chemical …, 2022 - pubs.rsc.org
Unravelling the atomic scale diffusion that can occur at the surface, at the interface or into
the bulk is challenging: multi-scale modelling approaches usually require intensive …

Toward in silico biomolecular manipulation through static modes: atomic scale characterization of HIV-1 protease flexibility

M Brut, A Estève, G Landa… - The Journal of Physical …, 2014 - ACS Publications
Probing biomolecular flexibility with atomic-scale resolution is a challenging task in current
computational biology for fundamental understanding and prediction of biomolecular …

Développement de systèmes miniaturisés à base d'aptamères pour la détection de biomarqueurs de cancer

S Bourg - 2019 - pastel.hal.science
Les méthodes habituelles de diagnostic du cancer sont invasives et coûteuses et permettent
rarement de dépister la maladie à un stade précoce. L'apparition de biomarqueurs de …

[PDF][PDF] EXAMINATION OF A DNA APTAMER (TLS11a) AS A CANCER-SPECIFIC TARGETING AGENT WITHIN CULTURED BNL 1ME A. 7R. 1 LIVER CANCER …

AS Melissa Sutton - 2014 - digital.library.txst.edu
Hepatocellular carcinoma (HCC), the most common form of liver cancer, kills over 650,000
people worldwide every year, primarily in regions where viral hepatitis infections are …

[PDF][PDF] Examination of a DNA Aptamer (TLS11a) as a Cancer-Specific Targeting Agent within Cultured BNL 1ME A. 7R. 1 Liver Cancer Cells

M Sutton - 2014 - digital.library.txstate.edu
Hepatocellular carcinoma (HCC), the most common form of liver cancer, kills over 650,000
people worldwide every year, primarily in regions where viral hepatitis infections are …