Intercellular Ca2+ Waves: Mechanisms and Function

L Leybaert, MJ Sanderson - Physiological reviews, 2012 - journals.physiology.org
Intercellular calcium (Ca2+) waves (ICWs) represent the propagation of increases in
intracellular Ca2+ through a syncytium of cells and appear to be a fundamental mechanism …

Astrocyte calcium waves: what they are and what they do

E Scemes, C Giaume - Glia, 2006 - Wiley Online Library
Several lines of evidence indicate that the elaborated calcium signals and the occurrence of
calcium waves in astrocytes provide these cells with a specific form of excitability. The …

ATP released from astrocytes mediates glial calcium waves

PB Guthrie, J Knappenberger, M Segal… - Journal of …, 1999 - Soc Neuroscience
Calcium waves represent a widespread form of intercellular communication. Although they
have been thought for a long time to require gap junctions, we recently demonstrated that …

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

JA Orellana, N Froger, P Ezan, JX Jiang… - Journal of …, 2011 - Wiley Online Library
J. Neurochem.(2011) 118, 826–840. Abstract Inflammation contributes to
neurodegeneration in post‐ischemic brain, diabetes, and Alzheimer's disease. Participants …

Cross talk between activation of microglia and astrocytes in pathological conditions in the central nervous system

W Liu, Y Tang, J Feng - Life sciences, 2011 - Elsevier
Microglia and astrocytes in the central nervous system are now recognized as active
participants in various pathological conditions such as trauma, stroke, or chronic …

Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS

JI Nagy, JE Rash - Brain Research Reviews, 2000 - Elsevier
This review article summarizes early and recent literature on the structure, distribution and
composition of gap junctions between astrocytes and oligodendrocytes, and the differential …

Gap junctions and connexin expression in the normal and pathological central nervous system

N Rouach, E Avignone, W Meme, A Koulakoff… - Biology of the …, 2002 - Wiley Online Library
Summry—Gap junctions are widely expressed in the various cell types of the central
nervous system. These specialized membrane intercellular junctions provide the …

[HTML][HTML] Defective gap junctional intercellular communication in the carcinogenic process

M Mesnil, S Crespin, JL Avanzo… - Biochimica et Biophysica …, 2005 - Elsevier
Gap junctions are membrane structures made of intercellular channels which permit the
diffusion from cytoplasm to cytoplasm of small hydrophilic molecules. Nearly 40 years ago …

Accelerated hippocampal spreading depression and enhanced locomotory activity in mice with astrocyte-directed inactivation of connexin43

M Theis, R Jauch, L Zhuo, D Speidel… - Journal of …, 2003 - Soc Neuroscience
Using a human glial fibrillary acidic protein (hGFAP) promoter-driven cre transgene, we
have achieved efficient inactivation of a floxed connexin43 (Cx43) gene in astrocytes of …

Intercellular calcium signaling and gap junctional communication in astrocytes

C Giaume, L Venance - Glia, 1998 - Wiley Online Library
Two main characteristics of astrocytes are their elaborated intracellular calcium signaling
and their high degree of intercellular communication mediated by gap junctional channels …