Function and regulation of the divisome for mitochondrial fission

F Kraus, K Roy, TJ Pucadyil, MT Ryan - Nature, 2021 - nature.com
Mitochondria form dynamic networks in the cell that are balanced by the flux of iterative
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …

Mitochondrial proteins: from biogenesis to functional networks

N Pfanner, B Warscheid, N Wiedemann - Nature reviews Molecular cell …, 2019 - nature.com
Mitochondria are essential for the viability of eukaryotic cells as they perform crucial
functions in bioenergetics, metabolism and signalling and have been associated with …

Mitochondrial dynamics: overview of molecular mechanisms

L Tilokani, S Nagashima, V Paupe… - Essays in …, 2018 - portlandpress.com
Mitochondria are highly dynamic organelles undergoing coordinated cycles of fission and
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …

Role of cardiolipin in mitochondrial function and dynamics in health and disease: molecular and pharmacological aspects

G Paradies, V Paradies, FM Ruggiero, G Petrosillo - Cells, 2019 - mdpi.com
In eukaryotic cells, mitochondria are involved in a large array of metabolic and bioenergetic
processes that are vital for cell survival. Phospholipids are the main building blocks of …

Drp1-dependent mitochondrial fission in cardiovascular disease

J Jin, X Wei, X Zhi, X Wang, D Meng - Acta Pharmacologica Sinica, 2021 - nature.com
Mitochondria are highly dynamic organelles undergoing cycles of fusion and fission to
modulate their morphology, distribution, and function, which are referred as 'mitochondrial …

Reactive oxygen species and mitochondrial dynamics: the yin and yang of mitochondrial dysfunction and cancer progression

J Ježek, KF Cooper, R Strich - Antioxidants, 2018 - mdpi.com
Mitochondria are organelles with a highly dynamic ultrastructure maintained by a delicate
equilibrium between its fission and fusion rates. Understanding the factors influencing this …

The connection between the dynamic remodeling of the mitochondrial network and the regulation of muscle mass

V Romanello, M Sandri - Cellular and Molecular Life Sciences, 2021 - Springer
The dynamic coordination of processes controlling the quality of the mitochondrial network is
crucial to maintain the function of mitochondria in skeletal muscle. Changes of mitochondrial …

Mitochondrial structure and bioenergetics in normal and disease conditions

M Protasoni, M Zeviani - International journal of molecular sciences, 2021 - mdpi.com
Mitochondria are ubiquitous intracellular organelles found in almost all eukaryotes and
involved in various aspects of cellular life, with a primary role in energy production. The …

Structural basis of mitochondrial receptor binding and constriction by DRP1

R Kalia, RYR Wang, A Yusuf, PV Thomas, DA Agard… - Nature, 2018 - nature.com
Mitochondrial inheritance, genome maintenance and metabolic adaptation depend on
organelle fission by dynamin-related protein 1 (DRP1) and its mitochondrial receptors …

Glaucomatous optic neuropathy: Mitochondrial dynamics, dysfunction and protection in retinal ganglion cells

WK Ju, GA Perkins, KY Kim, T Bastola, WY Choi… - Progress in Retinal and …, 2023 - Elsevier
Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by a
slow, progressive, and multifactorial degeneration of retinal ganglion cells (RGCs) and their …