The physiological role of estrogen in the female endometrium is well established. On the
basis of responses to steroid hormones (progesterone, androgen, and estrogen), the …

The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …

Endometriosis is a chronic, inflammatory, estrogen-dependent disease characterized by the
growth of endometrial tissue outside of the uterine cavity. Although the etiology of …

Imbalances in gut and reproductive tract microbiota composition, known as dysbiosis,
disrupt normal immune function, leading to the elevation of proinflammatory cytokines …

Endometriosis is a frequent and chronic inflammatory disease with impacts on reproduction,
health and quality of life. This disorder is highly estrogen-dependent and the purpose of …

Alterations in estrogen-mediated cellular signaling play an essential role in the
pathogenesis of endometriosis. In addition to higher estrogen receptor (ER) β levels …

Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-
coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian …

Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

Endometriosis is a gynecological disorder characterized by the growth of endometrial tissue
(glands and stroma) outside the uterus, mainly in the peritoneal cavity, ovaries, and …

Endometriosis is a hormone-dependent, chronic inflammatory condition that affects 5–10%
of reproductive-aged women. It is a complex disorder characterized by the growth of …