OBJECTIVE: To illustrate the necessity for an enhanced understanding of the genetic basis
of male factor infertility, to present a comprehensive synopsis of these genetic elements, and …

Male infertility is a common and complex problem affecting 1 in 20 men. Despite voluminous
research in this field, in many cases, the underlying causes are unknown. Epigenetic factors …

This article reports the results of the most recent in a series of EHSRE workshops designed
to synthesize the current state of the field in Andrology and provide recommendations for …

Background Male-factor infertility is a common condition, and etiology is unknown for a high
proportion of cases. Abnormal epigenetic programming of the germline is proposed as a …

The use of Assisted Reproductive Technologies (ARTs) in modern cattle breeding is an
important tool for improving the production of dairy and beef cattle. A frequently employed …

This study assessed sperm quality declining on relation to paternal age and its impact on in
vitro fertilization (IVF) outcomes in order to estimate the APA (Advanced Paternal Age) cutoff …

This article presents an update on the variable prognostic significance of different sperm
pathologies in patients with severe male factor infertility due to morphology and motility …

A precise packaging of the paternal genome during spermiogenesis is essential for
fertilization and embryogenesis. Most of the nucleosomal DNA supercoiling must be …

Advanced age has been reported to negatively affect sperm parameters and spermatozoa
DNA integrity. A decline in sperm criteria was also associated with altered epigenetic marks …

The profound architectural changes that transform spermatids into spermatozoa result in a
high degree of DNA packaging within the sperm head. However, the mature sperm …