It is important to understand the balance between cortical plasticity and stability in various
systems and across spatial scales in the adult brain. Here we review studies of adult …

A general theory of brain function has to be able to explain local and non-local network
computations over space and time. We propose a new framework to capture the key …

The visual cortex has the capacity for experience-dependent change, or cortical plasticity,
that is retained throughout life. Plasticity is invoked for encoding information during …

Biological structures can be seen as collections of special devices coordinated by a matrix of
organization. Devices are dif? cult to evolve and are meticulously conserved through the …

Objectives: To describe the hallucinations occurring as a result of a macular hole in each
eye and to investigate the neural basis. Methods: Psychophysical observations including …

While recent studies of synaptic stability in adult cerebral cortex have focused on dendrites,
how much axons change is unknown. We have used advances in axon labeling by viruses …

Vision loss after retinal or cerebral visual injury (CVI) was long considered to be irreversible.
However, there is considerable potential for vision restoration and recovery even in …

The functional architecture of adult cerebral cortex retains a capacity for experience-
dependent change. This is seen following focal binocular lesions, which induce rapid …

Age-related macular degeneration (AMD), affecting the retina, afflicts one out of ten people
aged 80 years or older in the United States. AMD often results in vision loss to the central 15 …

Studies of the effects of peripheral and central lesions, perceptual learning and
neurochemical modification on the sensory representations in cortex have had a dramatic …