Mediation analysis methods used in observational research: a scoping review and recommendations
Background Mediation analysis methodology underwent many advancements throughout
the years, with the most recent and important advancement being the development of causal …
the years, with the most recent and important advancement being the development of causal …
Analytical approaches to testing pathways linking greenspace to health: A scoping review of the empirical literature
Background Inadequate translation from theoretical to statistical models of the greenspace–
health relationship may lead to incorrect conclusions about the importance of some …
health relationship may lead to incorrect conclusions about the importance of some …
A guideline for reporting mediation analyses of randomized trials and observational studies: the AGReMA statement
Importance Mediation analyses of randomized trials and observational studies can generate
evidence about the mechanisms by which interventions and exposures may influence health …
evidence about the mechanisms by which interventions and exposures may influence health …
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma
Circular extrachromosomal DNA (ecDNA) in patient tumors is an important driver of
oncogenic gene expression, evolution of drug resistance and poor patient outcomes …
oncogenic gene expression, evolution of drug resistance and poor patient outcomes …
Demystifying prediction in mediation research and the use of specific indirect effects and indirect effect sizes
The maturing state of partial least squares structural equation modeling (PLS-SEM) research
has seen exceptional knowledge advances over the past decade. However, advances in …
has seen exceptional knowledge advances over the past decade. However, advances in …
Long-term exposure to air pollution and severe COVID-19 in Catalonia: a population-based cohort study
The association between long-term exposure to ambient air pollutants and severe COVID-
19 is uncertain. We followed 4,660,502 adults from the general population in 2020 in …
19 is uncertain. We followed 4,660,502 adults from the general population in 2020 in …
Potential kidney protection with liraglutide and semaglutide: exploratory mediation analysis
Aims To investigate whether effects on chronic kidney disease risk factors could explain the
apparent reduction in kidney outcomes (composite of macroalbuminuria, doubling of serum …
apparent reduction in kidney outcomes (composite of macroalbuminuria, doubling of serum …
The conduct and reporting of mediation analysis in recently published randomized controlled trials: results from a methodological systematic review
Objectives To describe the methodological characteristics of mediation analyses (MAs)
reported in recent randomized controlled trials (RCTs) and to propose recommendations on …
reported in recent randomized controlled trials (RCTs) and to propose recommendations on …
Statistical mediation analysis for models with a binary mediator and a binary outcome: The differences between causal and traditional mediation analysis
Mediation analysis is an important statistical method in prevention research, as it can be
used to determine effective intervention components. Traditional mediation analysis defines …
used to determine effective intervention components. Traditional mediation analysis defines …
Designing and undertaking randomised implementation trials: guide for researchers
Implementation science is the study of methods to promote the systematic uptake of
evidence based interventions into practice and policy to improve health. Despite the need …
evidence based interventions into practice and policy to improve health. Despite the need …