Pharmaceutical agents, drugs of abuse, and toxic substances have a large impact, positive
and negative, on modern society. Efforts to mitigate the side effects of pharmaceuticals and …

Synthetic molecular recognition systems are increasingly being used to solve applied
problems in the life sciences, and bio-targeted host–guest chemistry has rapidly arisen as a …

Poisons always have fascinated humankind. Initially considered as deleterious or
hazardous substances, the modern era has witnessed the controlled utilization of dangerous …

The use of anticholinesterases to reverse residual neuromuscular block at the end of
surgery became routine practice in the 1950s. These drugs could only be used when …

The development of a reversal agent that can rapidly reverse clinically used
nondepolarizing neuromuscular blocking agents (NMBAs) has long been a challenge. Here …

We report the synthesis, X‐ray crystal structure, and molecular recognition properties of
pillar [n] arene derivative P [6] AS, which we refer to as Pillar [6] MaxQ along with analogues …

Background Sugammadex reversal of neuromuscular block facilitates recovery of
neuromuscular function after surgery, but the drug is expensive. We evaluated the effects of …

Broad-spectrum agents for the reversal of residual curarization induced by neuromuscular
blocking agents are of great significance. Here, we report a highly water-soluble cucurbit [8] …

This article traces the development of acyclic cucurbit [n] uril‐type receptors with a focus on
work from the Isaacs group. First, we describe the synthesis of methylene bridged glycoluril …

We measured the affinity of five molecular container compounds (calabadions 1 and 2, CB
[7], sulfocalix [4] arene, and HP‐β‐CD) toward seven drugs of abuse in homogenous …