VEGF-a stimulus for neuronal development and regeneration in the CNS and PNS

V Theis, C Theiss - Current Protein and Peptide Science, 2018 - ingentaconnect.com
The vascular endothelial growth factor (VEGF) is a homodimeric disulfide bound
glycoprotein that promotes endothelial growth, accompanied by higher vascular …

Neurotrophic and antidepressant actions of brain-derived neurotrophic factor require vascular endothelial growth factor

S Deyama, E Bang, T Kato, XY Li, RS Duman - Biological psychiatry, 2019 - Elsevier
Background Activity-dependent release of brain-derived neurotrophic factor (BDNF) in the
medial prefrontal cortex (mPFC) is essential for the rapid and sustained antidepressant …

Mesenchymal stem cells in chemotherapy‐induced peripheral neuropathy: A new challenging approach that requires further investigations

KF Al‐Massri, LA Ahmed… - Journal of tissue …, 2020 - Wiley Online Library
Chemotherapeutic drugs may disrupt the nervous system and cause chemotherapy‐induced
peripheral neuropathy (CIPN) as side effects. There are no completely successful …

Interactions of Notch1 and TLR4 signaling pathways in DRG neurons of in vivo and in vitro models of diabetic neuropathy

T Chen, H Li, Y Yin, Y Zhang, Z Liu, H Liu - Scientific reports, 2017 - nature.com
Understanding the interactions between Notch1 and toll-like receptor 4 (TLR4) signaling
pathways in the development of diabetic peripheral neuropathy may lead to interpretation of …

Synaptic loss and firing alterations in Axotomized Motoneurons are restored by vascular endothelial growth factor (VEGF) and VEGF-B

PM Calvo, RR de la Cruz, AM Pastor - Experimental Neurology, 2018 - Elsevier
Vascular endothelial growth factor (VEGF), also known as VEGF-A, was discovered due to
its vasculogenic and angiogenic activity, but a neuroprotective role for VEGF was later …

Blocking VEGF by bevacizumab compromises electrophysiological and morphological properties of hippocampal neurons

P Latzer, O Shchyglo, T Hartl, V Matschke… - Frontiers in Cellular …, 2019 - frontiersin.org
A hallmark of glioblastoma multiforme (GBM) is neoangiogenesis, mediated by the
overexpression of vascular endothelial growth factor (VEGF). Anti-VEGF antibodies, like …

Stem Cell Factor (SCF) is a putative biomarker of antidepressant response

F Benedetti, S Poletti, TA Hoogenboezem… - Journal of Neuroimmune …, 2016 - Springer
Growth factors involved in neurogenesis and neuroplasticity could play a role in biological
processes that drive depression recovery. Combined total sleep deprivation and morning …

VEGF attenuates 2-VO induced cognitive impairment and neuronal injury associated with the activation of PI3K/Akt and Notch1 pathway

L Wang, F Wang, S Liu, X Yang, J Yang… - Experimental Gerontology, 2018 - Elsevier
Vascular endothelial growth factor (VEGF) has been identified as a potential treatment for
effectively improving cognitive function in several neuropathological conditions. However …

Notch1 participates in the activation of autophagy in the hippocampus of type I diabetic mice

Y Wang, S Wang, W Zhang, J Liu, Z Yang… - Neurochemistry …, 2021 - Elsevier
Notch1 not only plays a key role in the development of the nervous system but also
modulates synaptic plasticity and memory. However, the role of Notch1 in the brain of …

Voluntary running-enhanced synaptic plasticity, learning and memory are mediated by Notch1 signal pathway in C57BL mice

X Zhang, C Yang, J Gao, H Yin, H Zhang… - Brain Structure and …, 2018 - Springer
It is well known that voluntary running can enhance synaptic plasticity and improve learning
and memory abilities. The Notch1 receptor is also reported to be associated with these …