Medicinal chemistry of acridine and its analogues

P Prasher, M Sharma - MedChemComm, 2018 - pubs.rsc.org
'Acridine'along with its functional analogue 'Acridone'is the most privileged pharmacophore
in medicinal chemistry with diverse applications ranging from DNA intercalators …

Quinoline, quinazoline and acridone alkaloids

JP Michael - Natural product reports, 2003 - pubs.rsc.org
Covering: July 2001 to June 2002. Previous review: Nat. Prod. Rep., 2002, 19, 742 This
review covers the isolation, structure determination, synthesis and biological activity of …

Antiprotozoal activities of Colombian plants

B Weniger, S Robledo, GJ Arango, E Deharo… - Journal of …, 2001 - Elsevier
In our search for therapeutical alternatives for antiprotozoal chemotherapy, we collected a
selection of 44 plants from western Colombia upon ethnopharmacological and …

Molecular epidemiology of citrus leprosis virus c: a new viral lineage and phylodynamic of the main viral subpopulations in the americas

C Chabi-Jesus, PL Ramos-González… - Frontiers in …, 2021 - frontiersin.org
Despite the importance of viral strains/variants as agents of emerging diseases, genetic and
evolutionary processes affecting their ecology are not fully understood. To get insight into …

Niche for acridine derivatives in anticancer therapy

MR Galdino-Pitta, MGR Pitta, MCA Lima… - Mini Reviews in …, 2013 - benthamdirect.com
During the last 4 decades, intensive research has focussed on the effect of small organic
molecules with antitumour activity that are able to intercalate into DNA and inhibit …

Structure and in vitro antiparasitic activity of constituents of Citropsis articulata root bark

D Lacroix, S Prado, D Kamoga… - Journal of Natural …, 2011 - ACS Publications
From the results of an ethnomedicinal investigation of plants from Uganda with antimalarial
activity, Citropsis articulata was selected because of the antiplasmodial effect of an ethyl …

Acridone alkaloids as potent inhibitors of cathepsin V

RP Severino, RVC Guido, EF Marques… - Bioorganic & medicinal …, 2011 - Elsevier
Cathepsin V is a lysosomal cysteine peptidase highly expressed in thymus, testis and
corneal epithelium. Eleven acridone alkaloids were isolated from Swinglea glutinosa (Bl.) …

Acridone alkaloids

JP Michael - The Alkaloids: Chemistry and Biology, 2017 - Elsevier
There have been substantial developments in the chemistry and biology of the acridone
alkaloids in the 16 years since the topic was last reviewed in this series of monographs …

Metal-free regioselective formation of C–N and C–O bonds with the utilization of diaryliodonium salts in water: Facile synthesis of N-arylquinolones and …

MK Mehra, MP Tantak, V Arun, I Kumar… - Organic & Biomolecular …, 2017 - pubs.rsc.org
Regioselective construction of crucial C–N and C–O bonds leading to N-arylquinolones and
aryloxyquinolines has been accomplished by employing easily accessible diaryliodonium …

Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa

AFK Waffo, PH Coombes, NR Crouch, DA Mulholland… - Phytochemistry, 2007 - Elsevier
The combined hexane/CH2Cl2 extract of the stem bark of Teclea gerrardii (Rutaceae:
Toddalioideae) has yielded two acridone alkaloids, 3-hydroxy-1-methoxy-N-methylacridone …