Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

The revolution in cancer genomics has uncovered a variety of clinically relevant mutations in
primary brain tumours, creating an urgent need to develop non-invasive imaging biomarkers …

According to World Health Organization (WHO) estimates, cancer is responsible for more
deaths than all coronary heart disease or stroke worldwide, serving as a major public health …

With the recent emergence of novel technologies, the field of biomarker discovery has been
the subject of intense research and activity. Major advances in cancer control will be greatly …

Purpose: Medulloblastoma is the most common malignant brain tumor occurring in
childhood and is a significant cause of morbidity and mortality in pediatric oncology. More …

Biologically accurate mouse models of human cancer have become important tools for the
study of human disease. The anatomical location of various target organs, such as brain …

Mouse models have increased our understanding of the pathogenesis of medulloblastoma
(MB), the most common malignant pediatric brain tumor that often forms in the cerebellum. A …

Purpose A mouse model of Alzheimer's disease demonstrates reduced beta-amyloid levels
in the whole brain, associated with a gain of hippocampal memory, after drinking taurine …

The ongoing development of animal models of neurological and psychiatric disorders in
combination with the development of advanced nuclear magnetic resonance (NMR) …

Multinuclear ex vivo magnetic resonance spectroscopy (MRS) of cancer cells, xenografts,
human cancer tissue, and biofluids is a rapidly expanding field that is providing unique …