Understanding the phagocytosis of particles: the key for rational design of vaccines and therapeutics

S Moreno-Mendieta, D Guillén… - Pharmaceutical …, 2022 - Springer
A robust comprehension of phagocytosis is crucial for understanding its importance in innate
immunity. A detailed description of the molecular mechanisms that lead to the uptake and …

Structural optimization of platinum drugs to improve the drug-loading and antitumor efficacy of PLGA nanoparticles

MB Sokol, MV Chirkina, NG Yabbarov, MR Mollaeva… - Pharmaceutics, 2022 - mdpi.com
Currently, molecular dynamics simulation is being widely applied to predict drug–polymer
interaction, and to optimize drug delivery systems. Our study describes a combination of in …

Defining endocytic pathways of Fucoidan-coated PIBCA nanoparticles from the design of their surface architecture

MCB Lira-Nogueira, VP Gibson, V Nicolas… - Pharmaceutical …, 2022 - Springer
Purpose This work investigated the endocytic pathways taken by poly (isobutylcyanoacrylate
)(PIBCA) nanoparticles differing in their surface composition and architecture, assuming that …

Transfer phenomena of nanoliposomes by live imaging of primary cultures of cortical neurons

E Passeri, P Bun, K Elkhoury, M Linder, C Malaplate… - Pharmaceutics, 2022 - mdpi.com
Soft nanoparticles, and in particular, nanoliposomes (NL), have attracted increasing interest
for their use in food, nutraceuticals, and in particular, in pharmaceutics for drug delivery …

A ferrofluid with high specific absorption rate prepared in a single step using a biopolymer

DA Guzmán-Rocha, T Córdova-Fraga… - Materials, 2022 - mdpi.com
An exhaustive characterization of the physicochemical properties of gum arabic (GA)-coated
Fe3O4 magnetic nanoparticles was conducted in this work. These nanoparticles were …

Nano (bio) Materials Do Not Affect Macrophage Phenotype—A Study Conducted by the REFINE Project

CAW David, JP Vermeulen, S Gioria… - International Journal of …, 2024 - mdpi.com
Macrophages are well known for their involvement in the biocompatibility, as well as
biodistribution, of nano (bio) materials. Although there are a number of rodent cell lines, they …