The discovery of vitamin E will have its 100th anniversary in 2022, but we still have more
questions than answers regarding the biological functions and the essentiality of vitamin E …

Four tocopherols are available in nature and are absorbed with the diet, but only one RRR-α-
tocopherol satisfies the criteria of being a vitamin. The biological activity of the different …

Fats, oils or lipids consist of a large number of organic compounds including fatty acids,
monoacylglycerols, diacylglycerols, triacylglycerols (TGs), phospholipids (PLs), eicosanoids …

Tocopherols and tocotrienols, collectively known as tocochromanols, are lipid-soluble
molecules that belong to the group of vitamin E compounds and are essential in the human …

Glutamate-mediated excitotoxicity, neuroinflammation, and oxidative stress are common
underlying events in neurodegeneration. This pathogenic “triad” characterizes the …

The cancer-preventive activity of vitamin E has been studied. Whereas some
epidemiological studies have suggested a protective effect of vitamin E against cancer …

Vitamin E is the last of all vitamins whose essentiality is not yet understood. Its widely
accepted role as a lipophilic antioxidant has been questioned, since proof of its in vivo …

During the last 90 years since the discovery of vitamin E, research has focused on different
properties of this molecule, the focus often depending on the specific techniques and …

Nanoscale lipid bilayers, or nanoliposomes, are generally spherical vesicles formed by the
dispersion of phospholipid molecules in a water-based medium by energy input. The other …

Vitamin E modulates signal transduction pathways by several molecular mechanisms. As a
hydrophobic molecule located mainly in membranes it contributes together with other lipids …