RNA modifications in physiology and disease: towards clinical applications

S Delaunay, M Helm, M Frye - Nature Reviews Genetics, 2024 - nature.com
The ability of chemical modifications of single nucleotides to alter the electrostatic charge,
hydrophobic surface and base pairing of RNA molecules is exploited for the clinical use of …

Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications

J Li, C Wu, PK Chu, M Gelinsky - Materials Science and Engineering: R …, 2020 - Elsevier
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Role of extracellular matrix in development and cancer progression

C Walker, E Mojares, A del Río Hernández - International journal of …, 2018 - mdpi.com
The immense diversity of extracellular matrix (ECM) proteins confers distinct biochemical
and biophysical properties that influence cell phenotype. The ECM is highly dynamic as it is …

Advances in crosslinking strategies of biomedical hydrogels

W Hu, Z Wang, Y Xiao, S Zhang, J Wang - Biomaterials science, 2019 - pubs.rsc.org
Biomedical hydrogels as sole repair matrices or combined with pre-seeded cells and
bioactive growth factors are extensively applied in tissue engineering and regenerative …

Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

Tissue-specific decellularization methods: rationale and strategies to achieve regenerative compounds

U Mendibil, R Ruiz-Hernandez… - International journal of …, 2020 - mdpi.com
The extracellular matrix (ECM) is a complex network with multiple functions, including
specific functions during tissue regeneration. Precisely, the properties of the ECM have been …

The extracellular matrix in development

DAC Walma, KM Yamada - Development, 2020 - journals.biologists.com
As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides
both physical support and signaling regulation to cells. Some ECM molecules provide a …

Tailoring gelation mechanisms for advanced hydrogel applications

V Nele, JP Wojciechowski… - Advanced Functional …, 2020 - Wiley Online Library
Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …