1H-Detected Biomolecular NMR under Fast Magic-Angle Spinning

T Le Marchand, T Schubeis, M Bonaccorsi… - Chemical …, 2022 - ACS Publications
Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

Solid-state NMR: Methods for biological solids

S Ahlawat, KR Mote, NA Lakomek… - Chemical Reviews, 2022 - ACS Publications
In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

From angstroms to nanometers: measuring interatomic distances by solid-state NMR

AA Shcherbakov, J Medeiros-Silva, N Tran… - Chemical …, 2021 - ACS Publications
Internuclear distances represent one of the main structural constraints in molecular structure
determination using solid-state NMR spectroscopy, complementing chemical shifts and …

Proton detected solid-state NMR of membrane proteins at 28 Tesla (1.2 GHz) and 100 kHz magic-angle spinning

E Nimerovsky, KT Movellan, XC Zhang, MC Forster… - Biomolecules, 2021 - mdpi.com
The available magnetic field strength for high resolution NMR in persistent superconducting
magnets has recently improved from 23.5 to 28 Tesla, increasing the proton resonance …

Proton-based ultrafast magic angle spinning solid-state NMR spectroscopy

R Zhang, KH Mroue… - Accounts of chemical …, 2017 - ACS Publications
Conspectus Protons are vastly abundant in a wide range of exciting macromolecules and
thus can be a powerful probe to investigate the structure and dynamics at atomic resolution …

Bone hydration: How we can evaluate it, what can it tell us, and is it an effective therapeutic target?

RK Surowiec, MR Allen, JM Wallace - Bone reports, 2022 - Elsevier
Water constitutes roughly a quarter of the cortical bone by volume yet can greatly influence
mechanical properties and tissue quality. There is a growing appreciation for how water can …

1H‐Detected Solid‐State NMR Studies of Water‐Inaccessible Proteins In Vitro and In Situ

J Medeiros‐Silva, D Mance, M Daniëls… - Angewandte Chemie …, 2016 - Wiley Online Library
Abstract 1H detection can significantly improve solid‐state NMR spectral sensitivity and
thereby allows studying more complex proteins. However, the common prerequisite for 1H …

Selectively Enhanced 1H–1H Correlations in Proton-Detected Solid-State NMR under Ultrafast MAS Conditions

Z Zhang, A Oss, ML Org, A Samoson, M Li… - The journal of …, 2020 - ACS Publications
Proton-detected solid-state NMR has emerged as a powerful analytical technique in
structural elucidation via 1H–1H correlations, which are mostly established by broadband …

1H magic-angle spinning NMR evolves as a powerful new tool for membrane proteins

T Schubeis, T Le Marchand, LB Andreas… - Journal of Magnetic …, 2018 - Elsevier
Building on a decade of continuous advances of the community, the recent development of
very fast (60 kHz and above) magic-angle spinning (MAS) probes has revolutionised the …

Bone quality assessment techniques: geometric, compositional, and mechanical characterization from macroscale to nanoscale

HB Hunt, E Donnelly - Clinical reviews in bone and mineral metabolism, 2016 - Springer
This review presents an overview of the characterization techniques available to
experimentally evaluate bone quality, defined as the geometric and material factors that …