At present more than 250 FDA approved chlorine containing drugs were available in the
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …

Due to its appreciable diversity in biological actions, thiazole and its substituted
components, a significant class of heterocyclic compounds has developed as an influential …

A total of 52 novel 1, 2, 4-triazole thioether and thiazolo [3, 2-b]-1, 2, 4-triazole derivatives
bearing the 6-fluoroquinazolinyl moiety were designed, synthesized, and evaluated as …

Triazoles are nitrogen‐bearing heterocycles. In the last few decades, researchers have
focused on fused heterocycles, as they have better pharmacological effect compared to …

Thiazole and related nucleus are one of the most important potential entities in the largely
growing chemical world of heterocyclic compounds exhibiting remarkable pharmacological …

Sulfonamides constitute an important class of drugs, with many types of pharmacological
agents possessing antibacterial, anti-carbonic anhydrase, anti-obesity, diuretic …

Combating several pathological conditions associated with ureolytic enzyme (urease)
remains a formidable challenge because of the lack of effective and safe drug therapies. In …

Abstract Thiol-thione tautomerism of 1, 2, 4-triazole derivative with Schiff base was
investigated by spectroscopic methods and quantum mechanical calculations. Theoretical …

This study reports the synthesis of the novel crystalline 4-phenyl-3-((4-phenyl-1H-1, 2, 3-
triazol-1-yl) methyl)-1H-1, 2, 4-triazole-5 (4H)-thione compound in an excellent yield via …

Research and development for novel substances possessing anti-infective activity have
attracted considerable attention due to the escalating resistance towards conventional …