[HTML][HTML] Severe asthma and quality of life

E Hossny, L Caraballo, T Casale, Y El-Gamal… - World Allergy …, 2017 - Elsevier
Severe asthma has a great impact on the quality of life (QOL) of patients and their families.
The magnitude of this morbidity is affected by several personal factors including age …

The role of type 2 inflammation in the pathogenesis of asthma exacerbations

EM Dunican, JV Fahy - Annals of the American Thoracic Society, 2015 - atsjournals.org
Asthma exacerbations are an important cause of asthma morbidity. Although viral infection
of the upper airway is a common cause of asthma exacerbations, the reasons why some …

[PDF][PDF] Health‐related quality of life burden in severe asthma

VM McDonald, SA Hiles, KA Jones, VL Clark… - Medical Journal of …, 2018 - mja.com.au
It is largely unrecognised that the impacts of asthma are different in patients with severe
disease compared with patients with mild to moderate disease.• Severe asthma is …

[HTML][HTML] Estimating health-state utility for economic models in clinical studies: an ISPOR good research practices task force report

SE Wolowacz, A Briggs, V Belozeroff, P Clarke… - Value in Health, 2016 - Elsevier
Cost-utility models are increasingly used in many countries to establish whether the cost of a
new intervention can be justified in terms of health benefits. Health-state utility (HSU) …

[HTML][HTML] “Real-life” effectiveness of omalizumab in patients with severe persistent allergic asthma: the PERSIST study

G Brusselle, A Michils, R Louis, L Dupont… - Respiratory …, 2009 - Elsevier
OBJECTIVE: To evaluate the 16-and 52-week effectiveness of add-on omalizumab
treatment under real-life heterogeneity in patients, settings, and physicians in an open-label …

Exacerbation patterns in adults with asthma in England. A population-based study

CI Bloom, T Palmer, J Feary, JK Quint… - American journal of …, 2019 - atsjournals.org
Rationale: Asthma is heterogeneous and knowledge on exacerbation patterns is lacking.
Previous studies have had a relatively short follow-up or focused on severe disease …

It is time to change the way we manage mild asthma: an update in GINA 2019

J Muneswarao, MA Hassali, B Ibrahim, B Saini… - Respiratory …, 2019 - Springer
Asthma is a heterogeneous lung disease, usually characterised by chronic airway
inflammation. Although evidence-based treatments are available in most countries, asthma …

Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children

KM Kew, M Quinn, BS Quon… - Cochrane Database of …, 2016 - cochranelibrary.com
Background People with asthma may experience exacerbations or" attacks" during which
their symptoms worsen and additional treatment is required. Written action plans may …

Impact of asthma exacerbations and asthma triggers on asthma-related quality of life in patients with severe or difficult-to-treat asthma

AT Luskin, BE Chipps, L Rasouliyan, DP Miller… - The Journal of Allergy …, 2014 - Elsevier
Background Few data are available that evaluate the relationship among asthma
exacerbations, asthma triggers, and asthma-related quality of life (QoL). Objective To …

Smoking cessation medicines and e-cigarettes: a systematic review, network meta-analysis and cost-effectiveness analysis

KH Thomas, MN Dalili… - Health …, 2021 - research-information.bris.ac.uk
Background Cigarette smoking is one of the leading causes of early death. Varenicline
[Champix (UK), Pfizer Europe MA EEIG, Brussels, Belgium; or Chantix (USA), Pfizer Inc …