Ovarian cancer (OVCA) is the second most common gynecological cancer and one of the
leading causes of cancer related mortality among women. Recent studies suggest that …

Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to
improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects …

High-grade serous ovarian carcinoma (HGSOC) represents the most common form of
epithelial ovarian carcinoma. The absence of specific symptoms leads to late-stage …

Abstract Background Polygenic risk scores (PRSs) have been demonstrated to identify
women of European, Asian, and Latino ancestry at elevated risk of developing breast cancer …

Purpose: We recently reported that the transcription factor NFATC4, in response to
chemotherapy, drives cellular quiescence to increase ovarian cancer chemoresistance. The …

Epithelial ovarian cancer (EOC) is one of the deadliest gynecological cancers worldwide,
mainly because of its initially asymptomatic nature and consequently late diagnosis. Long …

Network medicine provides network theoretical tools, methods and properties to study
underlying laws governing human interactome to identify disease states and disease …

Purpose The causes for the survival disparity among Black women with epithelial ovarian
cancer (EOC) are likely multi-factorial. Here we describe the African American Cancer …

Objective Most women with epithelial ovarian cancer (EOC) are diagnosed after the disease
has metastasized and survival in this group remains poor. Circulating proteins associated …

Black women face the highest mortality-to-incidence ratio from high grade serous ovarian
cancer (HGSOC). This study investigated biological differences in HGSOC tumors from …