The Failure of R0

J Li, D Blakeley, RJ Smith? - Computational and mathematical …, 2011 - Wiley Online Library
The basic reproductive ratio, R0, is one of the fundamental concepts in mathematical
biology. It is a threshold parameter, intended to quantify the spread of disease by estimating …

[图书][B] An introduction to mathematical modeling of infectious diseases

MY Li - 2018 - Springer
Mathematical modeling has been increasingly recognized in the public health community as
an important research tool for infectious diseases control. Mathematical models are widely …

Dynamics of an HTLV-I infection model with delayed CTLs immune response

S Bera, S Khajanchi, TK Roy - Applied Mathematics and Computation, 2022 - Elsevier
This paper deals with a four dimensional mathematical model for Human T-cell leukemia
virus type-I (HTLV-I) infection that includes delayed CD8+ cytotoxic T-cells (CTLs) immune …

Bifurcation analysis of a mathematical model for malaria transmission

N Chitnis, JM Cushing, JM Hyman - SIAM Journal on Applied Mathematics, 2006 - SIAM
We present an ordinary differential equation mathematical model for the spread of malaria in
human and mosquito populations. Susceptible humans can be infected when they are bitten …

[HTML][HTML] Causes of backward bifurcations in some epidemiological models

AB Gumel - Journal of Mathematical Analysis and Applications, 2012 - Elsevier
The phenomenon of backward bifurcation in disease transmission models, where a stable
endemic equilibrium co-exists with a stable disease-free equilibrium when the associated …

Mathematical analysis of the transmission dynamics of HIV/TB coinfection in the presence of treatment

O Sharomi, CN Podder, AB Gumel… - Mathematical …, 2007 - aimsciences.org
This paper addresses the synergistic interaction between HIV and mycobacterium
tuberculosis using a deterministic model, which incorporates many of the essential …

Role of incidence function in vaccine-induced backward bifurcation in some HIV models

O Sharomi, CN Podder, AB Gumel, EH Elbasha… - Mathematical …, 2007 - Elsevier
The phenomenon of backward bifurcation in disease models, where a stable endemic
equilibrium co-exists with a stable disease-free equilibrium when the associated …

An SVEIRE model of tuberculosis to assess the effect of an imperfect vaccine and other exogenous factors

F Sulayman, FA Abdullah, MH Mohd - Mathematics, 2021 - mdpi.com
This study extends a deterministic mathematical model for the dynamics of tuberculosis
transmission to examine the impact of an imperfect vaccine and other exogenous factors …

Stability of an adaptive immunity pathogen dynamics model with latency and multiple delays

AM Elaiw, NH AlShamrani - Mathematical Methods in the …, 2018 - Wiley Online Library
We incorporate three distributed time delays into the model of pathogen dynamics with
antibody and Cytotoxic T Lymphocyte (CTL) immune responses. We consider both actively …

Analysis of a within-host HIV/HTLV-I co-infection model with immunity

AM Elaiw, NH Alshamrani - Virus Research, 2021 - Elsevier
Human immunodeficiency virus (HIV) and human T-lymphotropic virus type I (HTLV-I) are
two retroviruses that attack the immune cells and impair their functions. Both HIV and HTLV-I …