Insights on the inhibitory power of flavonoids on tyrosinase activity: A survey from 2016 to 2021

HAS El-Nashar, MIG El-Din, L Hritcu, OA Eldahshan - Molecules, 2021 - mdpi.com
Tyrosinase is a multifunctional copper-containing oxidase enzyme that initiates melanin
synthesis in humans. Excessive accumulation of melanin pigments or the overexpression of …

Anticancer potential of the plant‐derived Saponin Gracillin: a comprehensive review of mechanistic approaches

MS Bhuia, R Chowdhury, FA Sonia… - Chemistry & …, 2023 - Wiley Online Library
With the increasing prevalence of cancer and the toxic side effects of synthetic drugs, natural
products are being developed as promising therapeutic approaches. Gracillin is a naturally …

Neuroprotective effect of artichoke-based nanoformulation in sporadic Alzheimer's disease mouse model: focus on antioxidant, anti-inflammatory, and amyloidogenic …

HAS El-Nashar, H Abbas, M Zewail, MH Noureldin… - Pharmaceuticals, 2022 - mdpi.com
The vast socio-economic impact of Alzheimer's disease (AD) has prompted the search for
new neuroprotective agents with good tolerability and safety profile. With its outstanding role …

Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia

HAS El-Nashar, AM Sayed… - Journal of Enzyme …, 2023 - Taylor & Francis
Trypanosomiasis is a protozoan disease transmitted via Trypanosoma brucei. This study
aimed to examine the metabolic profile and anti-trypanosomal effect of methanol extract of …

[HTML][HTML] Phytochemical profiling and neuroprotective activity of Callistemon subulatus leaves against cyclophosphamide-induced chemobrain

O Rabie, HAS El-Nashar, MY George… - Biomedicine & …, 2023 - Elsevier
Cyclophosphamide (CPA) is a chemotherapeutic drug used for various types of cancers.
However, patients receiving CPA for long periods suffer cognitive impairment associated …

Chemical composition, seasonal variation and antiaging activities of essential oil from Callistemon subulatus leaves growing in Egypt

O Rabie, HAS El-Nashar, TA Majrashi… - Journal of enzyme …, 2023 - Taylor & Francis
Callistemon is an aromatic genus of flowering plants belonging to family Myrtaceae. The
essential oils of C. subulatus leaves were collected in four seasons and analyzed using …

Antioxidant and Pulmonary Protective Potential of Fraxinus xanthoxyloides Bark Extract against CCl4‐Induced Toxicity in Rats

T Younis, F Jabeen, A Hussain, B Rasool… - Chemistry & …, 2023 - Wiley Online Library
Fraxinus xanthoxyloides is a perennial shrub belonging to family Oleaceae, traditionally
used for malaria, jaundice, pneumonia, inflammation, and rheumatism. Our study is aimed to …

Genus Lupinus (Fabaceae): a review of ethnobotanical, phytochemical and biological studies

AR Ishaq, HAS El-Nashar, T Younis… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives Lupinus is a large and diverse genus comprising approximately 200 species,
belonging to the family Fabaceae. Lupinus plants have been used for heart stimulants …

Chemical Composition, Antiaging Activities and Molecular Docking Studies of Essential Oils from Acca sellowiana (Feijoa)

HAS El‐Nashar, M Adel, M El‐Shazly… - Chemistry & …, 2022 - Wiley Online Library
This study aimed to investigate the chemical composition of essential oils isolated from Acca
sellowiana (feijoa) leaves and stems and elaborate on their relevance as natural anti‐aging …

Chemical Constituents, Antioxidant, and Enzyme Inhibitory Activities Supported by In-Silico Study of n-Hexane Extract and Essential Oil of Guava Leaves

SH Aly, OA Eldahshan, ST Al-Rashood, FA Binjubair… - Molecules, 2022 - mdpi.com
Psidium guajava (Guava tree) is one of the most widely known species in the family
Myrtaceae. The Guava tree has been reported for its potential antioxidant, anti-inflammatory …