A single-cell atlas of the cycling murine ovary

ME Morris, MC Meinsohn, M Chauvin, HD Saatcioglu… - Elife, 2022 - elifesciences.org
The estrous cycle is regulated by rhythmic endocrine interactions of the nervous and
reproductive systems, which coordinate the hormonal and ovulatory functions of the ovary …

Follicular development and ovary aging: single-cell studies

H Zhao, Y Wang, Y Yang - Biology of Reproduction, 2023 - academic.oup.com
Follicular development is a critical process in reproductive biology that determines the
number of oocytes and interacts with various cells within the follicle (such as oocytes …

Oocyte quality following in vitro follicle development

J Xu, MB Zelinski - Biology of reproduction, 2022 - academic.oup.com
In vitro follicle development (IVFD) is an adequate model to obtain basic knowledge of
folliculogenesis and provides a tool for ovarian toxicity screening. IVFD yielding competent …

In-depth analysis of transcriptomes in ovarian cortical follicles from children and adults reveals interfollicular heterogeneity

I Rooda, J Hassan, J Hao, M Wagner… - Nature …, 2024 - nature.com
The ovarian cortical reserve of follicles is vital for fertility. Some medical treatments are toxic
to follicles, leading to premature ovarian insufficiency. Ovarian tissue cryopreservation is an …

Single-cell transcriptomics analysis of human small antral follicles

X Fan, I Moustakas, M Bialecka, JS Del Valle… - International journal of …, 2021 - mdpi.com
Human ovarian folliculogenesis is a highly regulated and complex process. Characterization
of follicular cell signatures during this dynamic process is important to understand follicle …

Decoding 11-oxygenated androgen synthesis: insights from enzyme gene expression and LC—MS/MS quantification

J Zheng, Y Wang, J Jiang, T Jin, Y Liu… - European Journal of …, 2024 - academic.oup.com
Background Adrenal-origin and peripheral tissue-transformed 11-oxygenated androgens
are recognized as significant androgens. However, our current understanding of the …

Single-cell transcriptomics analysis reveals a cell atlas and cell communication in yak ovary

J Pei, L Xiong, S Guo, X Wang, Y La, M Chu… - International Journal of …, 2023 - mdpi.com
Yaks (Bos grunniens) are the only bovine species that adapt well to the harsh high-altitude
environment in the Qinghai-Tibetan plateau. However, the reproductive adaptation to the …

Classification of Atretic Small Antral Follicles in the Human Ovary

F Wei, X Fan, JS Del Valle, JD Asseler… - International journal of …, 2023 - mdpi.com
The reproductive lifespan in humans is regulated by a delicate cyclical balance between
follicular recruitment and atresia in the ovary. The majority of the small antral follicles present …

Xenograft model of heterotopic transplantation of human ovarian cortical tissue and its clinical relevance

L Man, NL Guahmich, E Kallinos, L Park… - …, 2023 - rep.bioscientifica.com
In brief Xenografts of human ovarian cortical tissue provide a tractable model of heterotopic
autotransplantation that is used for fertility preservation in patients undergoing ablative …

Chronic superphysiologic AMH promotes premature luteinization of antral follicles in human ovarian xenografts

L Man, N Lustgarten Guahmich, E Kallinos… - Science …, 2022 - science.org
Anti-Müllerian hormone (AMH) is produced by growing ovarian follicles and provides a
diagnostic measure of reproductive reserve in women; however, the impact of AMH on …