To aid surgeons in more complete and safe resection of brain tumors, adjuvant technologies
have been developed to improve visualization of target tissue. Fluorescence-guided surgery …

5-Aminolevulinic acid (ALA) is a naturally occurring amino acid synthesized in all nucleated
mammalian cells. As a porphyrin precursor, ALA is metabolized in the heme biosynthetic …

Simple Summary Low-grade gliomas account for approximately 10–20% of all primary brain
tumors. Many techniques have been proposed to achieve a maximal safe resection, and …

One of the major issues in the surgical treatment of gliomas is the concern about maximizing
the extent of resection while minimizing neurological impairment. Thus, surgical planning by …

Simple Summary In the era of targeted therapies, achieving a maximal safe resection still
remains a critical prognosis factor in diffuse low-grade gliomas and represents the goal to …

Simple Summary Current literature debates the development and implementation of three-
dimensional Exoscopes in the daily routine of neurosurgical practice. This study evaluates …

Background Achieving maximal functionally safe resection of gliomas located within the
eloquent speech areas is challenging, and there is a lack of literature on the combined use …

Introduction: Recent advances in tumor visualization have improved the extent of resection
(EOR) of primary and secondary tumors of the central nervous system, while limiting the …

Background The prognosis of diffusely infiltrating glioma patients is dismal but varies greatly
between individuals. While characterization of gliomas primarily relied on histopathological …

The term “fluorescence” was first proposed nearly two centuries ago, yet its application in
clinical medicine has a relatively brief history coming to the fore in the past decade …