IgA nephropathy: an interesting autoimmune kidney disease
A Rajasekaran, BA Julian, DV Rizk - The American journal of the medical …, 2021 - Elsevier
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …
[HTML][HTML] KDIGO 2021 clinical practice guideline for the management of glomerular diseases
BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …
Evaluating a new international risk-prediction tool in IgA nephropathy
SJ Barbour, R Coppo, H Zhang, ZH Liu… - JAMA internal …, 2019 - jamanetwork.com
Importance Although IgA nephropathy (IgAN) is the most common glomerulonephritis in the
world, there is no validated tool to predict disease progression. This limits patient-specific …
world, there is no validated tool to predict disease progression. This limits patient-specific …
Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials
HJL Heerspink, T Greene, H Tighiouart… - The lancet Diabetes & …, 2019 - thelancet.com
Background Change in albuminuria has strong biological plausibility as a surrogate
endpoint for progression of chronic kidney disease, but empirical evidence to support its …
endpoint for progression of chronic kidney disease, but empirical evidence to support its …
[HTML][HTML] Current treatment of IgA nephropathy
IgA nephropathy (IgAN) is the most common type of glomerulonephritis in Asia and the
Western world. In most patients, it follows an asymptomatic to oligosymptomatic course and …
Western world. In most patients, it follows an asymptomatic to oligosymptomatic course and …
IgA nephropathy
Abstract Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis
that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but …
that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but …
[HTML][HTML] Management and treatment of glomerular diseases (part 1): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies …
J Floege, SJ Barbour, DC Cattran, JJ Hogan… - Kidney international, 2019 - Elsevier
The Kidney Disease: Improving Global Outcomes (KDIGO) initiative organized a
Controversies Conference on glomerular diseases in November 2017. The conference …
Controversies Conference on glomerular diseases in November 2017. The conference …
Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective
EC Murray, R Nosalski, N MacRitchie… - Cardiovascular …, 2021 - academic.oup.com
Both animal models and human observational and genetic studies have shown that immune
and inflammatory mechanisms play a key role in hypertension and its complications. We …
and inflammatory mechanisms play a key role in hypertension and its complications. We …
GFR slope as a surrogate end point for kidney disease progression in clinical trials: a meta-analysis of treatment effects of randomized controlled trials
LA Inker, HJL Heerspink, H Tighiouart… - Journal of the …, 2019 - journals.lww.com
Background Surrogate end points are needed to assess whether treatments are effective in
the early stages of CKD. GFR decline leads to kidney failure, but regulators have not …
the early stages of CKD. GFR decline leads to kidney failure, but regulators have not …