A field guide to eukaryotic transposable elements
JN Wells, C Feschotte - Annual review of genetics, 2020 - annualreviews.org
Transposable elements (TEs) are mobile DNA sequences that propagate within genomes.
Through diverse invasion strategies, TEs have come to occupy a substantial fraction of …
Through diverse invasion strategies, TEs have come to occupy a substantial fraction of …
Host–transposon interactions: conflict, cooperation, and cooption
RL Cosby, NC Chang, C Feschotte - Genes & development, 2019 - genesdev.cshlp.org
Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …
threaten genome integrity. As a result, several mechanisms appear to have emerged during …
Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility
INTRODUCTION The rhesus macaque (Macaca mulatta) is one of the most widely used
nonhuman primate (NHP) models for studying human biology and disease. As a …
nonhuman primate (NHP) models for studying human biology and disease. As a …
Transposable elements drive the evolution of metazoan zinc finger genes
JN Wells, NC Chang, J McCormick… - Genome …, 2023 - genome.cshlp.org
Cys2-His2 zinc finger genes (ZNFs) form the largest family of transcription factors in
metazoans. ZNF evolution is highly dynamic and characterized by the rapid expansion and …
metazoans. ZNF evolution is highly dynamic and characterized by the rapid expansion and …
The arms race between KRAB–zinc finger proteins and endogenous retroelements and its impact on mammals
M Bruno, M Mahgoub… - Annual Review of …, 2019 - annualreviews.org
Nearly half of the human genome consists of endogenous retroelements (EREs) and their
genetic remnants, a small fraction of which carry the potential to propagate in the host …
genetic remnants, a small fraction of which carry the potential to propagate in the host …
Landscape of evolutionary arms races between transposable elements and KRAB-ZFP family
Transposable elements (TEs) are mobile parasitic sequences that have expanded within the
host genome. It has been hypothesized that host organisms have expanded the Krüppel …
host genome. It has been hypothesized that host organisms have expanded the Krüppel …
The UCSC repeat browser allows discovery and visualization of evolutionary conflict across repeat families
JD Fernandes, A Zamudio-Hurtado, H Clawson… - Mobile DNA, 2020 - Springer
Background Nearly half the human genome consists of repeat elements, most of which are
retrotransposons, and many of which play important biological roles. However repeat …
retrotransposons, and many of which play important biological roles. However repeat …
Adaptive evolution of an essential telomere protein restricts telomeric retrotransposons
B Saint-Leandre, C Christopher, MT Levine - Elife, 2020 - elifesciences.org
Essential, conserved cellular processes depend not only on essential, strictly conserved
proteins but also on essential proteins that evolve rapidly. To probe this poorly understood …
proteins but also on essential proteins that evolve rapidly. To probe this poorly understood …
Quantifying the arms race between LINE-1 and KRAB-zinc finger genes through TECookbook
Z Zuo - NAR Genomics and Bioinformatics, 2023 - academic.oup.com
To defend against the invasion of transposons, hundreds of KRAB-zinc finger genes (ZNFs)
evolved to recognize and silence various repeat families specifically. However, most repeat …
evolved to recognize and silence various repeat families specifically. However, most repeat …