[HTML][HTML] Similar in vitro response of rat brain nerve terminals, colon preparations and COLO 205 cells to smoke particulate matter from different types of wood

K Paliienko, M Korbush, N Krisanova, N Pozdnyakova… - Neurotoxicology, 2022 - Elsevier
Major source of carbon-containing air born particular matter that significantly pollutes
environment and provokes development of neuropathology is forest fires and wood …

[HTML][HTML] Amphiphilic anti-SARS-CoV-2 drug remdesivir incorporates into the lipid bilayer and nerve terminal membranes influencing excitatory and inhibitory …

N Krisanova, N Pozdnyakova, A Pastukhov… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Remdesivir is a novel antiviral drug, which is active against the SARS-CoV-2 virus.
Remdesivir is known to accumulate in the brain but it is not clear whether it influences the …

GABAA receptor agonist cinazepam and its active metabolite 3-hydroxyphenazepam act differently at the presynaptic site

T Borisova, N Pozdnyakova, M Dudarenko… - European …, 2021 - Elsevier
Abstract Cinazepam C 19 H 14 BrClN 2 O 5,(“LevanaⓇ ІC”) a partial GABA A receptor
agonist, and its active metabolite 3-hydroxyphenazepam C 15 H 10 BrClN 2 O 2 were …

Distribution of GABAergic neurons and expression levels of GABA transporter 1 in the rat neocortex during the neonatal period after perinatal hypoxic exposure

LI Khozhai, VA Otellin - Journal of Evolutionary Biochemistry and …, 2022 - Springer
The aim of this work was to study the distribution of GABA-expressing neurons and the
expression level of GABA transporter 1 (GAT1) in different layers of the rat neocortex in the …

Development and validation of a liquid chromatography‐tandem mass spectrometry method with triple‐stage fragmentation to determine levetiracetam in epileptic …

Z Ji, L Yin, Y Li, X Yang, L Lin, L Liu… - Journal of …, 2021 - Wiley Online Library
Levetiracetam is an antiepileptic drug that is primarily approved by the Food and Drug
Administration for the treatment of focal and generalized seizures. This study describes the …

Levetiracetam reduced the basal excitability of the dentate gyrus without restoring impaired synaptic plasticity in rats with temporal lobe epilepsy

G González-H, IJ Contreras-García, K Sánchez-Huerta… - Brain Sciences, 2020 - mdpi.com
Temporal lobe epilepsy (TLE), the most common type of focal epilepsy, affects learning and
memory; these effects are thought to emerge from changes in synaptic plasticity …

Development of neuroprotection approaches for long-term space missions

AO Pastukhov, NV Krisanova… - Space Science …, 2022 - space-scitechjournal.org.ua
The aim of the study was to develop a strategy and methodology for neuroprotection during
long-term space missions, which is based on a comprehensive study of the impact of …

Проєкти з космічної біології в Україні: сучасні тенденції

ЄЛ КОРДЮМ - Космічна наука і технологія, 2023 - nasu-periodicals.org.ua
Анотація Подано короткий огляд результатів реалізації біологічних проектів Цільової
програми наукових космічних досліджень НАН України (2018–2022 рр.) за актуальними …

ХАРАКТЕР ЛОКАЛИЗАЦИИ GABA-ИММУНОПОЗИТИВНЫX НЕЙРОНОВ И УРОВЕНЬ ЭКСПРЕССИИ GAT1 ТРАНСПОРТЕРА GABA В НЕОКОРТЕКСЕ КРЫС …

ЛИ Хожай, ВА Отеллин - Журнал эволюционной биохимии и …, 2022 - rusjphysiol.org
Аннотация Целью работы было изучение распределения нейронов, содержащих
GABA, и уровня экспрессии GAT 1 в разных слоях неокортекса крыс в неонатальный …

[PDF][PDF] Perinatal hyPoxia and thalamus brain region: increased efficiency of antiePilePtic drug levetiracetam to inhibit gaba release from nerve terminals

MV DUDareNko, NG PozDNyakoVa - ukrbiochemjournal.org
Levetiracetam (LV), 2S-(2-oxo-1-pyrrolidiny1) butanamide, is an antiepileptic drug. The
exact mechanisms of anticonvulsant effects of LV remain unclear. In this study, rats (Wistar …