Retinitis pigmentosa (RP) is an important cause of irreversible blindness worldwide and
lacks effective treatment strategies. Although mutations are the primary cause of RP …

The outer blood-retina barrier (oBRB), crucial for the survival and the proper functioning of
the overlying retinal layers, is disrupted in numerous diseases affecting the retina, leading to …

Inherited retinal diseases, which include retinitis pigmentosa, are a family of genetic
disorders characterized by gradual rod-cone degeneration and vision loss, without effective …

Oxidative stress plays a central role in age‐related macular degeneration (AMD). Iron, a
potent generator of hydroxyl radicals through the Fenton reaction, has been implicated in …

Multiple gene mutations have been associated with inherited retinal dystrophies (IRDs).
Despite the spectrum of phenotypes caused by the distinct mutations, IRDs display common …

A hallmark of inherited retinal degenerative diseases such as retinitis pigmentosa (RP) is
progressive structural and functional remodeling of the remaining retinal cells as …

Brain plasticity is a well-established concept designating the ability of central nervous
system (CNS) neurons to rearrange as a result of learning, when adapting to changeable …

Retinitis pigmentosa (RP) is a family of genetically heterogeneous diseases still without a
cure. Despite the causative genetic mutation typically not expressed in cone photoreceptors …

Retinitis pigmentosa (RP) is the most common type of inherited retinal dystrophy. The course
of RP is irreversible and leads to progressive loss of vision. It is characterized by hypotrophic …

Retinitis pigmentosa (RP) is an inherited retinal disease in which there is a loss of cone-
mediated daylight vision. As there are> 100 disease genes, our goal is to preserve cone …