Cataract, a clouding of the lens, is the most common cause of blindness in the world. It has a
marked impact on the wellbeing and productivity of individuals and has a major economic …

Background Cataract is a blinding disease worldwide. It is an age-related disease that
mainly occurs in people over 65 years old. Cataract is also prevalent in patients with …

Background: The blockade of the progression or onset of pathological events is essential for
the homeostasis of an organism. Some common pathological mechanisms involving a wide …

Aims Chronic hyperglycemia triggers overproduction of AKR1B1 (aldo-keto reductase family
1 member B) and receptor for advanced glycation end product (RAGE), which causes …

In chronic peritoneal diseases, mesothelial-mesenchymal transition is determined by cues
from the extracellular environment rather than just the cellular genome. The transformation …

Purpose: Cataracts are a major cause of visual acuity deterioration in diabetes mellitus (DM)
in developed and developing countries. Studies have demonstrated that overproduction of …

Posterior capsule opacification (PCO) is a common complication after cataract surgery.
Residual lens epithelial cells (LECs) on the anterior lens capsule, after cataract surgery …

Injury to the ocular lens perturbs cell-cell and cell-capsule/basement membrane interactions
leading to a myriad of interconnected signaling events. These events include cell-adhesion …

Phacoemulsification combined with intraocular lens (IOL) implantation is the international
standard operation procedure for cataract and has been generalized worldwide. However …

Fibrosis is a major, but incompletely understood, component of many diseases. The most
common vision-disrupting complication of cataract surgery involves differentiation of residual …