A platform for the synthesis of corynantheine-type corynanthe alkaloids

Y Nam, AT Tam, ER Miller… - Journal of the American …, 2023 - ACS Publications
Corynantheine-type alkaloids are major components of the Mitragyna speciosa, also known
as kratom, that exhibit unique pharmacological activity. However, no universal method to …

Dearomative ipso-Cyclization to Spiropseudoindoxyls: An Extendable Approach To Access Indolo[3,2-c]quinolinones and Isocryptolepine

CR Reddy, A Theja, E Srinivasu, M Subbarao - Organic Letters, 2023 - ACS Publications
A metal-free oxidative intramolecular dearomative spirocyclization of indole-3-formyl-2-
carboxamides has been developed for the first time, affording spiropseudoindoxyls in good …

Emerging Conformational-Analysis Protocols from the RTCONF55-16K Reaction Thermochemistry Conformational Benchmark Set

BB Mészáros, K Kubicskó, DD Németh… - Journal of Chemical …, 2024 - ACS Publications
RTCONF55-16K is a new, reactive conformational data set based on cost-efficient methods
to assess different conformational analysis protocols. Our reference calculations …

Gold‐Catalysed 1, 2‐Difunctionalisation: Sulfoximines as N‐and O‐Transfer Reagents

AV Mackenroth, PW Antoni, F Shiri, C Bendel… - Angewandte … - Wiley Online Library
Among the nucleophilic oxidants employed in the gold‐catalysed oxidation of alkynes,
sulphur‐based reagents have played a substantial role since the beginning, granting access …

Az opioidkrízis egy lehetséges megoldása: új típusú fájdalomcsillapítók fejlesztése

P Angyal, S Varga, T Soós - Scientia et Securitas, 2024 - akjournals.com
An ongoing public health emergency, the opioid crisis is characterized by the pervasive
misuse and addiction to opioid substances, encompassing both prescription pain relievers …

Recent Advances in Sustainable Total Synthesis and Chiral Pool Strategies with Emphasis on (–)‐Sclareol in Natural Products Synthesis

A Selka, A Abidli, L Schiavo, L Jeanmart… - European Journal of … - Wiley Online Library
Starting materials for sustainable total synthesis often come from the chiral pool:
carbohydrates, cyclitols, amino acids, and terpenes. In the terpene family,(–)‐sclareol has …

Total Synthesis of (–)-Mitragynine Pseudoindoxyl

EM Carreira, LJ Sprenger - Synfacts, 2023 - thieme-connect.com
Total Synthesis of (–)-Mitragynine Pseudoindoxyl Page 1 © 2023. Thieme. All rights reserved.
Georg Thieme Verlag KG, Rüdigerstraße 14, 70469 Stuttgart, Germany 849 P. ANGYAL, K …