VY Lim, S Zehentmeier, C Fistonich, JP Pereira - Advances in immunology, 2017 - Elsevier
B lymphocytes develop from hematopoietic stem cells (HSCs) in specialized bone marrow niches composed of rare mesenchymal lineage stem/progenitor cells (MSPCs) and …
In jawed vertebrates, B lymphocytes are part of the adaptive branch of the exceptionally complex immune system, which protects the organism from pathogenic infections. B cells …
The pathogenesis of autoimmune diseases is poorly understood-this is explicit in our failure to effectively cure them. This thesis had two primary, interdependent, aims. The first was …
For adult mice and humans the bone marrow is of critical importance in the generation and function of B lymphocytes. It is here that B cells are born from early hematopoietic …