Hemophagocytic Lymphohistiocytosis (HLH) is a rare clinical condition characterized by
sustained but ineffective immune system activation, leading to severe and systemic …

Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory disorder characterized
by the inability to properly terminate an immune response. Familial HLH (FHLH) and related …

Abstract Current hemophagocytic lymphohistiocytosis 2004 (HLH-2004)–based diagnostic
criteria for familial hemophagocytic lymphohistiocytosis (FHL) are based on expert opinion …

Cytokine storm is an umbrella term that describes an inflammatory syndrome characterized
by elevated levels of circulating cytokines and hyperactivation of innate and/or adaptive …

Chronic granulomatous disease (CGD) is a rare inborn error of immunity that typically
manifests with infectious complications. As the name suggest though, inflammatory …

Hemophagocytic lymphohistiocytosis (HLH), a hyperinflammatory hyperferritinemic
syndrome, is triggered by various etiologies and diseases and can lead to multiorgan …

Hematologic malignancies (HMs) are a heterogeneous group of cancers impacting
individuals of all ages that have been increasingly recognized in association with various …

This literature review explores the pivotal roles of the Uncoordinated-13 (UNC13) protein
family, encompassing UNC13A, UNC13B, UNC13C, and UNC13D, in the pathogenesis of …

Hemophagocytic lymphohistiocytosis (HLH) is an autoimmune phenomenon characterized
by reactive hyperactivity of cytotoxic T cells and histiocytes, leading to hypercytokinemic …

Hemophagocytic lymphohistiocytosis (HLH) is a rare and potential life‐threatening clinical
syndrome that results from uncontrolled activation of the immune system. Secondary HLH …