Current trends on solid dispersions: past, present, and future

R Malkawi, WI Malkawi, Y Al-Mahmoud… - Advances in …, 2022 - Wiley Online Library
Solid dispersions have achieved significant interest as an effective means of enhancing the
dissolution rate and thus the bioavailability of a range of weakly water‐soluble drugs. Solid …

Current techniques of water solubility improvement for antioxidant compounds and their correlation with its activity: molecular pharmaceutics

A Budiman, A Rusdin, DL Aulifa - Antioxidants, 2023 - mdpi.com
The aqueous solubility of a drug is important in the oral formulation because the drug can be
absorbed from intestinal sites after being dissolved in the gastrointestinal fluid, leading to its …

Oral bioavailability enhancement and anti-fatigue assessment of the andrographolide loaded solid dispersion

CC Yen, YK Liang, CP Cheng, MC Hsu… - International journal of …, 2020 - mdpi.com
Andrographolide (AG), a major diterpene lactone isolated from Andrographis paniculata
(Burm. f.) Nees (Acanthaceae), possesses a wide spectrum of biological activities. However …

A Novel Polyvinylpyrrolidone-Stabilized Illite Microparticle with Enhanced Antioxidant and Antibacterial Effect

H Oh, JS Lee, HS Lee, D Sung, WI Choi - Polymers, 2021 - mdpi.com
Illite is a clay mineral that shows antioxidant and antibacterial activities because of the
abundance of important clay elements in its structure. However, illite has low bioactivity due …

Hydrogel Formulation of Usnic Acid and Antibacterial Activity Test Against Propionibacterium acne

L Fitriani, Afifah, F Ismed, A Bakhtiar - Scientia Pharmaceutica, 2019 - mdpi.com
Usnic acid is known for its remarkable antimicrobial activity. The aim of this research was to
formulate hydrogel of usnic acid and evaluate the antibacterial activity against …

Therapeutic applications of solid dispersions for drugs and new molecules: In vitro and in vivo activities

VS Oliveira, AS de Almeida, IS Albuquerque… - Pharmaceutics, 2020 - mdpi.com
This review aims to provide an overview of studies that address the use, in therapeutic
applications, of solid dispersions (SDs) with biological activities in vitro and/or in vivo mainly …

Preparation and Characterization of Usnic Acid Nanocrystals with the Wet Grinding Method Using a Planetary Ball Mill.

R Wahyuni, H Lucida, G Revilla… - Tropical Journal of …, 2024 - search.ebscohost.com
Usnic acid is a potential active pharmaceutical ingredient derived from Usnea sp. It has a
low bioavailability because of poor aqueous solubility. Particle size reduction by nanosizing …

Enhancement of Dissolution Rate of Piperine Using Solid Dispersion Approach and Evaluation of Its Antioxidant Activity

RT Dewi, MFA Shiddiqi, V Hapsari, RA Naulidia… - Trends in …, 2025 - tis.wu.ac.th
Piperine is a phenolic compound in black pepper (Piper nigrum Linn) and Piper longum. It
has been used in traditional medicine and has many pharmacological properties. However …

Inclusion complexation of usnic acid-Hydroxypropyl-β-cyclodextrin: Physicochemical characterization and dissolution rate studies

M Fadhila, S Effendy, SH Siregar - Research Journal of …, 2024 - indianjournals.com
With antiviral, antiproliferative, anti-inflammatory, and analgesic effects, usnic acid is an
effective antimicrobial agent against human and plant diseases. The purpose of this study …

Membrane of Usnic Acid in Solid Dispersion and Effectiveness in Burn Healing

L Fitriani, B Fista, F Ismed, E Zaini - 2nd International Conference …, 2021 - atlantis-press.com
Usnic acid, a yellow crystalline of secondary metabolite of Usnea sp., has been known for its
tremendous pharmacological activities including antibacterial and anti-inflammatory …