The advent of RNA-sequencing (RNA-Seq) technologies has markedly improved our
knowledge and expanded the compendium of small non-coding RNAs, most of which derive …

tRNA fragments (tRFs) and tRNA halves have been implicated in various cellular processes,
including gene silencing, translation, stress granule assembly, cell differentiation …

RNA fragments deriving from tRNAs (tRFs) exist in all branches of life and the repertoire of
their biological functions regularly increases. Paradoxically, their biogenesis remains …

For a very long time, RNA molecules were treated as transistory molecules, by which the
genetic information flows from DNA to proteins; the model proposed in the 1960s accepted …

Recent transcriptome-wide studies have identified a diverse pool of transfer RNA (tRNA)-
derived RNAs or tRNA-derived fragments (tRFs). Some of these RNAs have been …

Ribosome-associated noncoding (ranc) RNAs are a novel class of short regulatory RNAs
with functions and origins that have not been well studied. In this present study, we …

Abstract tRNA-derived fragments (tRFs), which by definition are cleaved from tRNAs,
comprise a novel class of regulatory small non-coding RNAs. Recent evidence has revealed …

ABSTRACT tRNA-derived small fragments (tRFs) and tRNA halves have emerging functions
in different biological pathways, such as regulating gene expression, protein translation …

Recently, a number of ribosome-associated non-coding RNAs (rancRNAs) have been
discovered in all three domains of life. In our previous studies, we have described several …

We propose that ribosomal RNA (rRNA) formed the basis of the first cellular genomes, and
provide evidence from a review of relevant literature and proteonomic tests. We have …