In the era of personalized medicine and targeted therapies for the management of patients
with cancer, ultrasensitive detection methods for tumor genotyping, such as next-generation …

Digital droplet PCR (ddPCR) is a recent version of quantitative PCR (QT-PCR), useful for
measuring gene expression, doing clonality assays and detecting hot spot mutations. In …

Focal malformations of cortical development including focal cortical dysplasia,
hemimegalencephaly and megalencephaly, are a spectrum of neurodevelopmental …

Virus-specific T-cells (VSTs) from third-party donors mediate short-and long-term antiviral
effects in allogeneic hematopoietic stem cell transplant (HSCT) recipients with relapsed or …

Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …

This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

The digital polymerase chain reaction (dPCR) is considered to be the third-generation
polymerase chain reaction (PCR), as it yields direct, absolute and precise measures of …

New techniques are on the horizon for the detection of small leukemic clones in both, acute
leukemias and myeloproliferative disorders. A promising approach is based on digital …

Hematopoietic stem cell transplantation (HSCT) is a curative treatment for most hematologic
diseases. To evaluate the level of donor engraftment, chimerism must be carefully monitored …

Primary central nervous system lymphoma (PCNSL) occurring following organ
transplantation (post-transplantation lymphoproliferative disorder [PTLD]) is a highly …