Highlights•Psoriasis pathogenesis involved cytokines, microbial peptides, genetic
disposition.•Psoriasis is autoimmune disorder that affects approximately 125 million …

Adipokines are the primary mediators of adipose tissue-induced and regulated systemic
inflammatory diseases; however, recent findings revealed that serum levels of various …

Colorectal cancer (CRC) is known to be resistant to immunotherapy. In our phase-I clinical
trial, one patient achieved a 313-day prolonged response during the combined treatment of …

Vaspin expression is increased in white adipose tissue (WAT) of diet-induced obese mice
and rats and is supposed to compensate HFD-induced inflammatory processes and insulin …

Atopic dermatitis (AD) is characterized by chronic, relapsing, pruritic skin inflammation and
does not have a well-understood pathogenesis. In this study, we addressed the contribution …

Visceral adipose tissue-derived serine protease inhibitor (vaspin) or SERPINA12 according
to the serpin nomenclature was identified together with other genes and gene products that …

Human skin equivalents (HSEs) are three‐dimensional skin organ culture models raised in
vitro. This review gives an overview of common techniques for setting up HSEs. The HSE …

The purpose of our study was to investigate the effect of vaspin on myocardial ischemia
reperfusion injury (MIRI) and explore the underlying mechanism. The MIRI model was …

Background Psoriasis is a chronic immune-mediated skin condition with several types of
manifestation, including psoriatic arthritis. In recent years, studies have demonstrated …

Vaspin, also known as visceral adipose tissue-derived serine protease inhibitor; expression
of this adipokine has been confirmed in many parts of the body like the hypothalamus …