Systems and methods for determining nucleic acids

X Zhuang, KH Chen, A Boettiger, JR Moffitt… - US Patent …, 2021 - Google Patents
The present invention generally relates to systems and methods for imaging or determining
nucleic acids, for instance, within cells. In some embodiments, the transcriptome of a cell …

Confocal imaging using astigmatism

E Lampert, I Glaser-Inbari - US Patent 9,717,402, 2017 - Google Patents
The present disclosure provides computing device implemented methods, apparatuses, and
computing device readable media for confocal imaging using astigmatism. Confocal …

Methods and systems for three dimensional optical imaging, sensing, particle localization and manipulation

R Piestun, SA Quirin - US Patent 8,620,065, 2013 - Google Patents
Embodiments include methods, systems, and/or devices that may be used to image, obtain
three-dimensional information from a scence, and/or locate multiple small particles and/or …

3D imaging, ranging, and/or tracking using active illumination and point spread function engineering

R Piestun - US Patent 9,967,541, 2018 - Google Patents
Imaging systems and imaging methods are disclosed to estimate a three-dimensional
position of an object at a scene and/or generate a three-dimensional image of the scene …

Imaging or measurement methods and systems

R Piestun, A Agrawal, S Quirin, A Barsic… - US Patent …, 2021 - Google Patents
Imaging or measurement methods and systems including methods and systems for finding
the three-dimensional orientation and position of multiple dipole-like particles and single …

Multi-wavelength phase mask

Y Shechtman, WE Moerner, L Weiss - US Patent 10,341,640, 2019 - Google Patents
US10341640B2 - Multi-wavelength phase mask - Google Patents US10341640B2 - Multi-wavelength
phase mask - Google Patents Multi-wavelength phase mask Download PDF Info Publication …

Apparatuses and methods for three-dimensional imaging of an object

Y Shechtman, WE Moerner, L Weiss… - US Patent 10,187,626, 2019 - Google Patents
Various embodiments include an apparatus including a phase mask and circuitry. The
phase mask is configured and arranged with optics in an optical path to modify a shape of …

High-resolution scanning microscopy

I Kleppe, R Netz, T Kalkbrenner… - US Patent …, 2018 - Google Patents
A microscope and method for high resolution scanning microscopy of a sample, having: an
illumination device for the purpose of illuminating the sample, an imaging device for the …

Method and apparatus for single-particle localization using wavelet analysis

JB Sibarita - US Patent 9,117,273, 2015 - Google Patents
2013-01-22 Assigned to CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
reassignment CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) …

3D localisation microscopy and 4D localisation microscopy and tracking methods and systems

C Soeller, DM Baddeley, MB Cannell - US Patent 9,523,846, 2016 - Google Patents
(57) ABSTRACT A 3D localization microscopy system, 4D localization microscopy system, or
an emitter tracking system arranged to cause a phase difference between light passing to or …