As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …

Mortality from colorectal cancer is reduced through screening and early detection; moreover,
removal of neoplastic lesions can reduce cancer incidence. While understanding of the risk …

Histopathologic assessment is indispensable for diagnosing colorectal cancer (CRC).
However, manual evaluation of the diseased tissues under the microscope cannot reliably …

Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …

In addition to the adenoma to carcinoma sequence, colorectal carcinogenesis can occur via
the serrated pathway. Studies have focused on clarification of categories and molecular …

Initial results by Le and colleagues, which were published in the June 25, 2015 issue of the
New England Journal of Medicine, report significant responses of cancers with microsatellite …

Malignant pleural mesothelioma (MPM) is an aggressive cancer with rising incidence and
challenging clinical management. Through a large series of whole-genome sequencing …

Objective Accumulating evidence links the intestinal microbiota and colorectal
carcinogenesis. Fusobacterium nucleatum may promote colorectal tumour growth and …

Colon cancer is the third most common cancer worldwide. Most colorectal cancer
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …

Importance Evidence indicates a complex link between gut microbiome, immunity, and
intestinal tumorigenesis. To target the microbiota and immunity for colorectal cancer …