Albumin pre-opsonized membrane-active iPep nanomedicine potentiates chemo to immunotherapy of cancer

S Ji, L Huang, S Chang, X Sun, H Liu, A Li, Y Jin, H Fei - Biomaterials, 2023 - Elsevier
Chemotherapy-conjugated immunotherapy in clinical oncology conceptually resembles the
combined effects of cytoreduction and immunostimulation in membrane targeted cell killings …

The matricellular protein CCN3 supports lung endothelial homeostasis and function

KR Betageri, PA Link, AJ Haak… - … of Physiology-Lung …, 2023 - journals.physiology.org
Aberrant vascular remodeling contributes to the progression of many aging-associated
diseases, including idiopathic pulmonary fibrosis (IPF), where heterogeneous capillary …

Salvianolic acid A alleviates H2O2-induced endothelial oxidative injury via miR-204-5p

X Qiao, S Cao, S Chen, Y Guo, N Chen, Y Zheng… - Scientific Reports, 2024 - nature.com
Oxidative stress induced endothelial dysfunction plays a particularly important role in
promoting the development of cardiovascular diseases (CVDs). Salvianolic acid A (SalA) is …

Protective and curative effects of unconjugated bilirubin on gene expression of LOX-1 and iNOS in the heart of rats receiving high-fat diet and low dose streptozotocin …

MH Maleki, O Vakili, R Tavakoli, E Nadimi, Z Noori… - Journal of …, 2024 - Springer
Background Atherosclerosis is a chronic inflammatory condition affecting the large arteries
and is a major cause of cardiovascular diseases (CVDs) globally. Increased levels of …

hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia

D Pal, H Blair, J Parker, S Hockney, M Beckett… - Cell Reports …, 2022 - cell.com
Leukemia cells re-program their microenvironment to augment blast proliferation and
enhance treatment resistance. Means of clinically targeting such niche-driven treatment …

[HTML][HTML] RBT-1 reduces blood product utilization in patients undergoing nonemergency coronary artery bypass grafting and/or valve surgery

CA Mack, M Jessen, A Lamy, AK Khanna, K Lobdell… - JTCVS Open, 2024 - Elsevier
Study Design The underlying study was a Phase 2, multicenter, randomized, double-blind,
placebo-controlled trial. 5 Patients were randomized 1: 1: 1 to receive low dose RBT-1 (45 …