Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

This proceeding article compiles current research on the development of boron delivery
drugs for boron neutron capture therapy that was presented and discussed at the National …

Haloarenes have been an important class of chemicals in the modern organic chemistry
field because the halide functionality offers numerous possible transformations. Classical …

Boron neutron capture therapy (BNCT) is a binary type of radiotherapy for the treatment of
cancer. Due to recent developments of neutron accelerators and their installation in some …

Specifically addressing cell surface molecules on cancer cells facilitates targeted cancer
therapies that offer the potential to selectively destroy malignant cells, while sparing healthy …

Carborane is a carbon-boron molecular cluster that can be viewed as a 3D analog of
benzene. It features special physical and chemical properties, and thus has the potential to …

G-protein-coupled receptors like the human Y1 receptor (hY1R) are promising targets in
cancer therapy due to their high overexpression on cancer cells and their ability to …

Derivatives of dicarba-closo-dodecaboranes and dicarba-nido-undecaboranes (carboranes)
are of increasing interest for modern medicinal chemistry and materials science. The …

Boron neutron capture therapy (BNCT) is a radiotherapeutic modality based on the nuclear
capture of slow neutrons by stable 10B atoms followed by charged particle emission that …

Boron neutron capture therapy (BNCT) allows the selective elimination of malignant tumor
cells without affecting healthy tissue. Although this binary radiotherapy approach has been …