The antiretroviral treatment (ART) developed to control HIV infection led to a revolution in the
prognosis of people living with HIV (PLWH). PLWH underwent from suffering severe disease …

Eradication of latent human immunodeficiency virus (HIV) infection is a global health
challenge. Reactivation of HIV latency and killing of virus-infected cells, the so-called “kick …

Chronic HIV‐infected children suffer from premature aging and aging‐related diseases. Viral
replication induces an ongoing inflammation process, with the release of pathogen …

Background Tenofovir is a potent inhibitor of human telomerase. The clinical relevance of
this inhibition is unknown. Methods A prospective cohort of human immunodeficiency virus …

Background Tenofovir is a potent inhibitor of human telomerase. The clinical relevance of
this inhibition is unknown. Methods NEAT001/ANRS143 is a randomized trial that showed …

Human telomerase reverse transcriptase (hTERT) is an enzyme that is critically involved in
elongating and maintaining telomeres length to control cell life span and replicative …

Background: Data on accelerated aging in HIV-infected children are limited. In this study, we
assess 2 biomarkers of aging—telomere length and DNA methylation (DNAm) age—in a …

Aging, a time-dependent loss of physiological function, and its drivers are turning into a
significant topic of research as the population's mean age increases. Epigenetic alterations …

Objectives Our aim was to investigate factors associated with baseline blood telomere
length in participants enrolled in NEAT 001/ANRS 143, a randomized, open‐label trial …

The cause of cancer is attributed to the uncontrolled growth and proliferation of cells
resulting from genetic changes and alterations in cell behavior, a phenomenon known as …