The diversity of tumours with microsatellite instability: molecular mechanisms and impact upon microsatellite instability testing and mismatch repair protein …

J Shia - Histopathology, 2021 - Wiley Online Library
Microsatellite instability (MSI) as a distinct molecular phenotype in human neoplasms was
first recognised in 1993. Since then there has been tremendous progress in our …

Enhanced bone remodeling after fracture priming

JL Ramirez-GarciaLuna, K Rangel-Berridi… - Calcified Tissue …, 2022 - Springer
The immune system is an active component of bone repair. Mast cells influence the
recruitment of macrophages, osteoclasts and blood vessels into the repair tissue. We …

Genomic landscape of diploid and aneuploid microsatellite stable early onset colorectal cancer

Y Zhou, X Chen, J Chen, CD Kendrick… - Scientific reports, 2024 - nature.com
Although colorectal cancer (CRC) remains the second leading cause of cancer-related
death in the United States, the overall incidence and mortality from the disease have …

Unique evolutionary trajectories of breast cancers with distinct genomic and spatial heterogeneity

TN Phung, TH Webster, E Lenkiewicz, S Malasi… - Scientific reports, 2021 - nature.com
Breast cancers exhibit intratumoral heterogeneity associated with disease progression and
therapeutic resistance. To define the sources and the extent of heterogeneity, we performed …