Background Patients with primary biliary cholangitis who have an inadequate response to
therapy with ursodeoxycholic acid are at high risk for disease progression. Fibrates, which …

Choledochoscopy, or cholangioscopy, is an endoscopic procedure for direct visualization
within the biliary tract for diagnostic or therapeutic purposes. Since its conception in 1879 …

Portal vein thrombosis (PVT) is a frequent complication in cirrhotic patients, but it may also
exist as a basic vascular condition even without any liver damage. Local and systemic …

Introduction Primary sclerosing cholangitis (PSC) is a bile duct disorder characterized by
ductular reaction, hepatic inflammation, and liver fibrosis. The pathogenesis of PSC is still …

Liver fibrosis is characterized by excessive deposition of extracellular matrix due to chronic
inflammation of the liver. Hepatic stellate cells (HSCs) become activated and produce …

An aberrant activity of growth factor receptors followed by excessive cell proliferation plays a
significant role in pathogenesis of cholangitis. Therefore, inhibition of these processes could …

Bile duct constriction disrupts bile acid flow causing cholestasis causing hepatic necrosis,
fibrosis, and cirrhosis. The study investigated hepatoprotective effectiveness of Ayurvedic …

Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are biliary tract
pathologies with increased risk of HCC, although HCC is more commonly associated with …

Cholestatic liver diseases (CLDs) are a group of diseases characterized by jaundice and
cholestasis as the main presentation with different complications, which have considerable …

Autoimmune liver diseases are characterized by immune-mediated inflammation and
eventual destruction of the hepatocytes and the biliary epithelial cells. They can progress to …