X Yuan, J Zhang, F Xie, W Tan, S Wang… - Kidney and Blood …, 2017 - karger.com
Background/Aims: Renal tubulointerstitial fibrosis (TIF) is the common pathway of progressive chronic kidney disease. Inflammation has been widely accepted as the major …
J Schmitt, S Eckardt, PG Schlegel, AL Sirén… - Molecular …, 2015 - Springer
Parent-of-origin imprints have been implicated in the regulation of neural differentiation and brain development. Previously we have shown that, despite the lack of a paternal genome …
W Zhang, Q Wei - Biochemical and biophysical research communications, 2011 - Elsevier
Calcineurin is the only Ca 2+-dependent serine/threonine-specific protein phosphatase and is considered a potential regulator of many intracellular signaling events. In this study we …
T Doetschman, A Sholl, H dau rw Chen, C Gard… - Clinical …, 2011 - Elsevier
Calcineurin (CN) is a phosphatase that activates nuclear factor of activated T cells (NFAT). While the CN inhibitors cyclosporine A (CsA) and tacrolimus (FK506) can prevent graft …
Chronic inflammatory conditions such as Crohn's disease (CD) and Ulcerative colitis (UC) are risk factors for colon cancer. TGFβ has been shown to be dysregulated in colon cancer …
Spinal cord injury (SCI) is a devastating condition without a cure. The SCI process comprises an initially mechanical trauma and a secondary cascade of events including a …